Clinical Research Nurse

4 weeks ago


Hamilton, Ontario, Canada McMaster University Full time

Job Summary:

The Clinical Research Nurse (I) at McMaster University is responsible for planning, assessing, implementing, and evaluating protocol procedures and managing the daily operations of clinical research studies. This role ensures that all aspects of the study protocol are adhered to, and coordinates all aspects of the project related to managing a patient from study entry to completion of a follow-up. The successful candidate will require specialized, professional nursing care knowledge in the clinical area and knowledge of research principles and practices.

Purpose and Key Functions:

  • Develop and implement clinical research protocols.
  • Participate in the development and authoring of research protocols.
  • Troubleshoot problems at all stages of project development and implementation.
  • Conduct patient assessments to determine eligibility for participation in research studies.
  • Monitor patients for adverse reactions and respond appropriately.
  • Communicate with family members and caregivers regarding the disease process and the benefits of clinical studies.
  • Liaise between the clinic centre and remote clinic sites and personnel.
  • Process information and recognize problems with patients to intervene appropriately.
  • Analyze and process information to ensure the accuracy and appropriateness of patient management.
  • Ensure that research methodology is applied and all research material is handled in accordance with established protocols, policies, and procedures.
  • Conduct study-specific assessments of patients to determine suitability for projects and degree of disease acuity.
  • Apply specialized knowledge and scientific principles to review and interpret published literature.
  • Empathize with study patients and be attentive to their needs.
  • Recruit patients and enlist agencies to refer patients.
  • Review referrals and track intakes from various referral sources.
  • Design promotional strategies and related materials to encourage participation and support for the research study.
  • Facilitate focus group sessions with study patients.
  • Write sections of scientific papers, funding proposals, abstracts, and Research Ethics Board submissions.
  • Design and develop various forms, data reports, and letters required for the study.
  • Document and analyze patient responses and adverse events that may be experienced by a patient during the study.
  • Document and maintain patient consult notes, assessments, drug accountability logs, charts, and histories on each patient.
  • Plan and coordinate studies across multiple sites.
  • Develop estimates of time and resources for research projects.
  • Use statistical software to analyze data and interpret results.
  • Complete various calculations such as medication doses, safety values for clinical testing, and drug formulas.
  • Develop presentations and present information and training sessions to study personnel and patients.
  • Retrieve and respond to results of diagnostic tests.
  • Keep study participants informed of study progress through regular reports and newsletters.
  • Implement and maintain study budgets. Create financial projections and make adjustments to study budgets throughout the fiscal year.
  • Exercise appropriate controls, monitor, and reconcile accounts.
  • Responsible for the accurate collection of relevant data and ensure that all events are identified and properly recorded and that necessary confidentiality is maintained.
  • Collect, verify, evaluate, and record all patient study data.
  • Update and maintain information in a variety of databases and spreadsheets.
  • Gather, compile, and submit all pertinent documents such as physician and nursing licenses, curriculum vitae for all staff involved in the study, Food and Drug Administration forms, and Research Ethics Board documents, prior to the start of a clinical study.
  • Arrange for the safe and orderly exit of patients from the study.
  • Accountable to the College of Nurses of Ontario for all actions taken with study patients and must practice according to the Regulated Health Professions Act and the Standards of Practice for Nurses in Ontario.
  • Conduct literature searches.
  • May be required to perform specific medical procedures such as, venipuncture, pipetting samples, and administering medication by injection.
  • May be required to set up and monitor various medical devices such as intravenous and electrocardiogram equipment.
  • Collaborate with hospital administrators to facilitate the introduction of study protocol procedures within their departments.
  • Coordinate the procurement of equipment, supplies and data collection forms.
  • Inform patient and family about study protocols and procedures.
  • Explain benefits, risks and schedules prior to obtaining informed consent. Obtain formal, informed, and signed consent.
  • Abide by and adhere to hospital partners' policies and procedures with regards to various sources of information such as health records and databases.
  • Maintain the confidentiality of patient files and study data.
  • File and maintain a variety of documents such as source documentation, case report forms, and clinical records according to established regulations.


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