Senior Scientist – Pharmacokinetics Expert

3 weeks ago


Vancouver, British Columbia, Canada AbCellera Full time

At AbCellera, we are pushing the boundaries of conventional drug development to accelerate the discovery and development of antibody-based medicines. Our team of scientists, engineers, and experts is dedicated to advancing science and technology to improve human lives.

We are seeking an exceptional Senior Scientist – Pharmacokinetics to join our team. As a key member of our pharmacokinetics group, you will play a critical role in building out our capabilities to predict therapeutic responses to human disease. You will work closely with our protein science and protein engineering colleagues to identify the best antibodies for the job and develop fit-for-purpose bioanalytical methods.

Key Responsibilities:

  • Predicting and verifying appropriate dosing regimens to demonstrate antibody PK/PD relationships across a range of drug targets and disease areas
  • Developing bioanalytical strategies and establishing bioanalytical methods for protein therapeutics that are stage-appropriate (early research, GLP, etc)
  • Running pharmacokinetics studies to support antibody design and assessment
  • Designing and executing in vivo PK data packages tailored for individual programs
  • Collaborating with teams across the company to generate data and interpret them
  • Training and mentoring more junior scientists
  • Evaluating new technology and testing new models to better predict human illness
  • Reporting findings to our teams and partners to support data-driven decision making

Requirements:

  • A proven track record of building and interpreting bioanalytical datasets for antibodies
  • Expertise in designing PK studies and conducting PK/PD data analysis, using WinNonlin or other similar software
  • A PhD in Biology, Pharmacology, or related discipline with 5-8 years of experience in an industry setting; or a MSc with 8-10 years of relevant experience in an industry setting
  • Excellent communication and documentation skills, with the ability to communicate complex scientific and technical concepts to both technical and non-technical audiences
  • Experience authoring sections of regulatory submissions and a strong understanding of scientific and regulatory standards for bioassays of biologics

What We Offer:

AbCellera offers a competitive salary range of CAD $110,000 - $137,600 annually, commensurate with your education and job-related knowledge, skills, and experience. In addition to base salary, we offer equity, annual bonus dependent on team and company performance, and a 6% (non-match) RRSP contribution. You will also receive a CAD $1,500 annual Active Lifestyle Allowance, annual vacation, professional development opportunities, and comprehensive health benefits.

About AbCellera:

AbCellera is a global company that discovers and develops antibody-based medicines to help people live longer, happier, and more productive lives. We are focused on bringing innovative medicines to patients, both by advancing our internal pipeline of programs and partnering with companies that have novel science or innovative technology.

We are a team of idealists who are passionate about advancing science and technology to improve human lives. We look for people with drive and energy, who are genuinely curious and enjoy discussing innovative ideas in a highly collaborative and fast-paced environment.

To Apply:

Please submit your application through our website and refer to Job ID 23212 in your cover letter. We apologize in advance, but we receive a large volume of applications and are only able to contact those who are selected for an interview.



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