Research Scientist

4 weeks ago

Vancouver, British Columbia, Canada AbCellera Full time

About the Role:

We are seeking a highly motivated Research Scientist with a strong background in bioanalytical methods for antibodies or proteins to join our Pharmacokinetics team at AbCellera. In this role, you will be based in the lab and have the opportunity to help build out pharm-tox capabilities supporting lead antibody identification and progression into the clinic.

Key Responsibilities:

  • Designing and running in vivo pharmacokinetics studies across a diverse portfolio of antibody development programs
  • Generating pharmacokinetic and pharmacodynamic data from biological samples to critically assess the promise of individual antibody programs
  • Developing, qualifying, and implementing ligand binding assays for PK, TK, ADA, and PD support in various species and biological matrices
  • Liaising with external CROs to execute in vivo studies and for generation and characterization of assay critical reagents
  • Collaborating with teams across the company to solve problems, analyze, interpret, and communicate data
  • Training and mentoring more junior scientists
  • Growing your technical skill set and engaging in professional development
  • Preparing and authoring materials to educate colleagues and communicate strategies, key findings, and implications

Requirements:

  • Experience with pharmacokinetics analysis and interpretation, ideally in an industry setting, and a strong understanding of antibody structure and function
  • A PhD in a relevant field or a MSc with at least 5 years of work experience in an industrial or academic wet lab environment
  • Experience running pharmacokinetic studies and analyzing pharmacokinetic data, and demonstrated expertise with assay qualification and process optimization
  • Exceptional analytical and problem-solving capabilities, as well as excellent documentation, organizational, and communication skills
  • Proven interpersonal skills with the ability to work collaboratively as a member of a cross-functional team
  • Experience working with LC-MS for the quantification of large molecules in biological samples is desirable

About AbCellera:

AbCellera is a global company that discovers and develops antibody-based medicines to help people live longer, happier, and more productive lives. We are focused on bringing innovative medicines to patients by advancing our internal pipeline of programs and partnering with companies that have novel science or innovative technology.

We look for people with drive and energy, idealists who are passionate about advancing science and technology to bring better therapies to patients. If you are a highly motivated and self-directed individual with a strong background in bioanalytical methods, we encourage you to apply for this exciting opportunity.

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