Senior Research Scientist

4 weeks ago


Vancouver, British Columbia, Canada AbCellera Full time

We are seeking a highly motivated Senior Research Scientist with a strong background in oncology and immunology to join our team at AbCellera. As a key member of our research team, you will contribute to the assessment and development of antibody-based oncology drug candidates, working closely with our internal R&D team and external collaborators.

Key Responsibilities:

  • Lead internal preclinical in vivo oncology models to support oncology programs
  • Design, run, and interpret pharmacology studies to generate in vivo proof-of-concept and build confidence in selection of molecules for clinical development
  • Collaborate with in vitro biology, protein engineering, and pharmacokinetics scientists, as well as external CROs and collaborators, to execute efficient PK/PD studies to identify lead molecules and advance programs to human trials
  • Mentor team members in laboratory techniques related to tumour xenograft models
  • Report findings to internal program team and partners to support data-driven decisions
  • Evaluate available preclinical and clinical data sets to build testable biological hypotheses for oncology targets and then preclinically assess those hypotheses
  • Develop, perform, and oversee supporting assays to assess target modulation and downstream effects at the cellular, protein, and gene level

Requirements:

  • 8+ years of hands-on experience in oncology, immuno-oncology, and biologics drug development
  • PhD in Pharmacology, Immunology, or related field with 5-8 years of experience in an industry setting; or MSc with 8-10 years of relevant experience in an industry setting
  • Proven interpersonal skills and ability to create value on cross-functional teams
  • Genuine curiosity and interest in discussing innovative ideas in a highly collaborative and fast-paced environment
  • Ability to communicate scientific and/or technical concepts with an emphasis on application
  • Ability to independently identify project needs and follow up with constructing and implementing solutions
  • Enjoyment of teamwork and building data sets that help predict the success of therapies

What We Offer:

AbCellera offers a competitive salary range of CAD $110,000 - $137,600 annually, commensurate with education and job-related knowledge, skills, and experience. In addition to base salary, we offer equity, annual bonus dependent on team and company performance, and a 6% (non-match) RRSP contribution. You will also receive a CAD $1,500 annual Active Lifestyle Allowance, annual vacation, professional development opportunities, and comprehensive health benefits.

About AbCellera:

AbCellera is a global company that discovers and develops antibody-based medicines to help people live longer, happier, and more productive lives. We are focused on bringing innovative medicines to patients, both by advancing our internal pipeline of programs and partnering with companies that have novel science or innovative technology.

We look for people with drive and energy, idealists who are passionate about pushing the limits of science and technology to bring better therapies to patients.



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