Senior Bioprocess Development Scientist

1 week ago


Toronto, Ontario, Canada Pyramid Consulting, Inc Full time

Company Overview:

Pyramid Consulting, Inc. is a leading pharmaceutical industry expert providing innovative solutions to clients worldwide.

Estimated Salary:$120,000 - $180,000 per year

Job Description:

We are currently seeking an experienced Principal Scientist I for a 11+ month contract opportunity in Toronto, Ontario, Canada. This role will be located onsite and offers long-term potential.

The successful candidate will join the Vaccine Drug Substance Development (VDSD) team within the Global Bioprocess Development (GBD) department, actively supporting process development of novel vaccine candidates utilizing techniques such as molecular engineering, viral cell culture, bacterial fermentation, molecular biology, and supportive analytical techniques.

This individual will also interact with the Global Antigen Design team to screen new vaccine candidates, design and improve various constructs through molecular engineering techniques, and perform genetic stability testing.

In addition, they will conduct in-house or coordinate supportive analytical testing, including viral titration assays, FACS, SDS-PAGE, Western blot, HPLC, protein assays, and others.

Responsibilities include performing statistical data analysis, preparing technical reports and stakeholder presentations, contributing to tech transfer of processes to Global Clinical manufacturing or Manufacturing Sciences and Technology, and ensuring compliance with client's GxP quality, documentation requirements, and HSE policies.

Required Skills and Qualifications:

  • Molecular cloning (nucleic acid analysis and protein expression)
  • Experience with mammalian cell culture (e.g., SF9, CHO, Vero)
  • Analytical techniques such as virus titration assays, FACS, protein assays, SDS-PAGE, Western blot, HPLC, and others
  • Hands-on experience in molecular engineering tools (molecular cloning, nucleic acid analysis, and protein expression)
  • Computer skills: Word, Excel, PowerPoint
  • Statistical analysis and software (JMP, GraphPad Prism etc.) would be an asset
  • PhD with 1+ years' experience or MSc with 3+ years' experience in Biochemical Engineering/Life Sciences/Biology/Immunology/Biochemistry disciplines
  • English proficiency

Benefits:

Employee benefits include health insurance (medical, dental, vision), 401(k) plan, and paid sick leave (depending on work location).



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