Principal Scientist I

2 weeks ago

Toronto Ontario, Ontario, Canada Pyramid Consulting, Inc Full time

Immediate need for a talented Principal Scientist I. This is a 11+months contract opportunity with long-term potential and is located in Toronto, Ontario,Canada(Onsite). Please review the job description below and contact me ASAP if you are interested.


Job ID:24-48958

Pay Range: $35 - $40/hour. Employee benefits include, but are not limited to, health insurance (medical, dental, vision), 401(k) plan, and paid sick leave (depending on work location).

Key Responsibilities:


  • Department Description: The Vaccine Drug Substance Development (VDSD) within the Global Bioprocess Development (GBD) department actively supports process development of novel vaccine candidates utilizing techniques such as molecular engineering, viral cell culture, bacterial fermentation, molecular biology and supportive analytical techniques. Novel vaccine candidate are typically recombinant proteins produced in bacterial expression systems or attenuated viruses / glycosylated proteins produced in mammalian expressions system. In VDSD, we develop and scale up upstream and downstream processes for new vaccines up to 200L scale. Working within one of the most highly regulated industries, the candidate will have the opportunity to develop the ability to lead and function creatively within a team, while maintaining attention to strict compliance. The candidate will acquire knowledge of industry constraints and regulations.
  • Interphase with Global Antigen Design team to screen new vaccine candidate, design and improve various constructs through molecular engineering techniques and perform genetic stability testing.
  • Collaborate with Upstream Scientists and lead a team of Technologists to plan and execute upstream process optimization and scale-up studies using technologies such as AMBR high-throughput bioreactor system, small and pilot scale bioreactors.
  • Perform in-house or coordinate supportive analytical testing including viral titration assays, FACS, SDS-PAGE, Western blot, HPLC, protein assays, and others.
  • Perform statistical data analysis, prepare technical reports and stakeholder presentations.
  • Lead and/or contribute to characterization studies using Design of Experiments methodology.
  • Contribute to tech transfer of processes to Global Clinical manufacturing or Manufacturing Sciences and Technology.
  • Contribute to client’s digital initiatives (eg. AI).
  • Ensure compliance with client’s GxP quality, documentation requirements and HSE policies.


Key Requirements and Technology Experience:


  • Key Skills: molecular cloning, protein expression, mammalian cell culture .
  • Manager Notes: Must Have experience: molecular cloning (nucleic acid analysis, and protein expression), Experience with mammalian cell culture (eg. SF9, CHO, Vero) and Analytical techniques such as virus titration assays, FACS, protein assays, SDS-PAGE, Western blot, HPLC, and others .
  • Hands-on experience in molecular engineering tools (molecular cloning, nucleic acid analysis, and protein expression).
  • Knowledge and experience with bioprocessing methods and process scale-up.
  • Mandatory Computer skills: Word, Excel, Powerpoint.
  • Expertise in Statistical analysis and software (JMP, GraphPad Prism etc) would be an asset..
  • Soft skills ,Leadership skills ,Superior organizational skills .
  • Demonstrated accountability and motivation
  • Strong attention to detail and analytical skills
  • Excellent communication and interpersonal skills
  • Desire to work within a team environment
  • Recommended PhD with 1+ years’ experience or MSc with 3+ years’ experience in a Biochemical Engineering / Life Sciences / Biology / Immunology / Biochemistry disciplines
  • Languages: English proficiency.


Our client is a leading Pharmaceutical Industry, and we are currently interviewing to fill this and other similar contract positions. If you are interested in this position, please apply online for immediate consideration.


Pyramid Consulting, Inc. provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, colour, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.


By applying to our jobs you agree to receive calls, AI-generated calls, text messages, or emails from Pyramid Consulting, Inc. and its affiliates, and contracted partners. Frequency varies for text messages. Message and data rates may apply. Carriers are not liable for delayed or undelivered messages. You can reply STOP to cancel and HELP for help. You can access our privacy policy here.

  • Principal Applied AI Scientist

    3 weeks ago

    Toronto, Ontario, C6A, Ontario, Canada Microsoft Canada Full time

    Security represents the most critical priorities for our customers in a world awash in digital threats, regulatory scrutiny, and estate complexity. Microsoft Security aspires to make the world a safer place for all. We want to reshape security and empower every user, customer, and developer with a security cloud that protects them with end to end, simplified...

  • Senior Data Scientist I

    4 weeks ago

    Toronto, Ontario, Canada LexisNexis Risk Solutions Full time

    About the RoleWe are seeking a highly skilled Senior Data Scientist I to join our team at LexisNexis Legal & Professional. As a key member of our analytics team, you will be responsible for developing and implementing advanced analytical techniques to extract insights from complex data sets.ResponsibilitiesLead and conduct advanced data analysis to drive...

  • Principal Applied Scientist

    1 month ago

    Toronto, Ontario, Canada Ripple Full time

    About the RoleRipple is seeking a highly skilled Principal Applied Scientist to join our team. As a key member of our applied science pillar, you will be responsible for designing and building automated ML-based systems for forecasting, optimizing, and managing access to global liquidity. Your work will enable our customers to send value instantly, easily,...

  • Senior Data Scientist I

    4 weeks ago

    Old Toronto, Ontario, Canada LexisNexis Risk Solutions Full time

    About the RoleWe are seeking a highly skilled Senior Data Scientist I to join our team at LexisNexis Legal & Professional. As a key member of our data science team, you will be responsible for developing and implementing advanced analytical techniques to extract insights from complex data sets.ResponsibilitiesLeading and conducting advanced data analysis to...

  • Scientist I, Formulation Development Specialist

    2 months ago

    Toronto, Ontario, Canada BlueRock Therapeutics Full time

    Job Title: Scientist I, Formulation DevelopmentBlueRock Therapeutics is seeking a highly motivated and innovative Scientist to join our team in the development of cryopreservation procedures and methodologies for various iPSC-derived cell therapy products and intermediates.Key Responsibilities:Design, execute, and interpret cryoformulation and fill/finish...

  • Principal Data Scientist II

    4 weeks ago

    Toronto, Ontario, Canada Seismic Full time

    Job Title: Principal Data Scientist II - AI ArchitectSeismic is seeking a highly skilled Principal Data Scientist II - AI Architect to join our team. As a key member of our AI team, you will play a crucial role in shaping the AI strategy and driving the development of innovative AI solutions across our platform.Key Responsibilities:Define and drive the AI...

  • Research Technician I Position

    1 month ago

    Toronto, Ontario, Canada University Health Network Full time

    Job Title: Research Technician IUniversity Health Network is seeking a highly motivated and detail-oriented Research Technician I to join our team in the Molecular and Cellular Biology department. As a Research Technician I, you will be responsible for performing experiments, maintaining detailed records, and contributing to the development of new research...

  • **Data Scientist: Innovator in Artificial Intelligence**

    7 days ago

    Toronto, Ontario, Canada AGIQUANTRON TECHNOLOGIES INC. Full time

    Job SummaryAGIQUANTRON TECHNOLOGIES INC. is seeking a skilled Data Scientist to leverage machine learning and AI techniques to drive business decision making.Key ResponsibilitiesBuild predictive models to identify trends and patterns in large datasetsConduct research to ensure data suitability and availabilityCommunicate results to both technical and...

  • Senior Bioanalytical Scientist

    4 weeks ago

    Toronto, Ontario, Canada Pharma Medica Research Inc. Full time

    Job Title: Senior Bioanalytical ScientistPharma Medica Research Inc. is a leading contract research organization specializing in early phase clinical trials. We are seeking a highly skilled Senior Bioanalytical Scientist to join our team.Job SummaryThe Senior Bioanalytical Scientist will be responsible for leading bioanalytical functions in support of drug...

  • Scientist I, Formulation Development Specialist

    4 weeks ago

    Toronto, Ontario, Canada BlueRock Therapeutics Full time

    Job Summary:BlueRock Therapeutics is seeking a highly motivated and innovative Scientist I to join our team in the development of cryopreservation procedures and methodologies for various iPSC-derived cell therapy products and intermediates. The successful candidate will work closely with our cross-functional matrix to establish development tools, including...

  • Medical Scientist, HIV Therapeutic Area

    1 month ago

    Toronto, Ontario, Canada Gilead Sciences Full time

    Job Title: Medical Scientist, HIV Therapeutic AreaJob Summary:Gilead Sciences is seeking a knowledgeable and motivated Medical Scientist to join our team in the HIV therapeutic area. As a Medical Scientist, you will be responsible for implementing defined goals and objectives aligned with the Medical Affairs Plan of Action and other strategic initiatives...

  • Senior Data Scientist I

    4 weeks ago

    Toronto, Ontario, Canada LexisNexis Group Full time

    About Our TeamLexisNexis Legal & Professional is a global leader in providing information-based analytics and business insight solutions to professionals in the legal, risk management, and corporate sectors.Job DescriptionWe are seeking a highly skilled Data Scientist to join our team and contribute to the development of cutting-edge products that drive...

  • Principal Research Scientist

    2 days ago

    Toronto, Ontario, Canada University of Toronto Full time

    About the Role:The Department of Chemistry at the University of Toronto invites applications for a part-time Principal Research Scientist position in nanomaterials and diffraction-based sensing. The successful candidate will contribute to research projects led by a principal investigator, utilizing their expertise and experience to drive innovation.Job...

  • Scientist I, Formulation Development Specialist

    4 weeks ago

    Toronto, Ontario, Canada BlueRock Therapeutics Full time

    Job Summary:BlueRock Therapeutics is seeking a highly skilled Scientist I, Formulation Development to join our team. As a key member of our Process Development group, you will be responsible for developing and optimizing cryopreservation procedures and methodologies for various iPSC-derived cell therapy products and intermediates.Key Responsibilities:Design,...

  • Scientist I, Formulation Development Specialist

    3 weeks ago

    Toronto, Ontario, Canada BlueRock Therapeutics Full time

    Job Summary:BlueRock Therapeutics is seeking a highly motivated and innovative Scientist I to participate in the development of cryopreservation procedures and methodologies for various iPSC-derived cell therapy products and intermediates.Key Responsibilities:Design, execute, and interpret cryoformulation and fill/finish development experiments in...

  • Medical Scientist, HIV Therapeutic Area

    2 months ago

    Toronto, Ontario, Canada Gilead Sciences Full time

    Job Title: Medical Scientist, HIV Therapeutic AreaJob Summary:Gilead Sciences is seeking a highly motivated and knowledgeable Medical Scientist to join our team in the HIV therapeutic area. As a Medical Scientist, you will be responsible for implementing defined goals and objectives aligned with the Medical Affairs Plan of Action and other strategic...

  • AI Architect and Data Scientist Leader

    20 hours ago

    Toronto, Ontario, Canada Seismic Full time

    About the RoleWe are seeking a highly skilled AI Architect and Data Scientist to join our team as a Principal Data Scientist II – AI Architect. This role will play a crucial part in shaping our AI strategy, driving the development of innovative AI solutions, and collaborating with cross-functional teams to design, architect, build, and integrate advanced...

  • Senior Data Scientist I

    4 weeks ago

    Old Toronto, Ontario, Canada LexisNexis Risk Solutions Full time

    About the RoleWe are seeking a highly skilled Senior Data Scientist to join our team at LexisNexis Legal & Professional. As a Senior Data Scientist, you will be responsible for leading and conducting advanced data analysis to drive business insights and decision-making. Your role will involve developing and implementing machine learning algorithms to solve...

  • Senior Staff Scientist

    4 weeks ago

    Toronto, Ontario, Canada University of Toronto Full time

    Job Title: Senior Staff ScientistWe are seeking a highly skilled and experienced Senior Staff Scientist to join our team at the University of Toronto's Acceleration Consortium. As a key member of our research team, you will play a critical role in advancing the field of AI-driven autonomous discovery and developing materials and molecules required to address...

  • Senior Staff Scientist

    1 month ago

    Toronto, Ontario, Canada University of Toronto Full time

    Job Title: Senior Staff Scientist - AI and AutomationWe are seeking a highly skilled and experienced Senior Staff Scientist to join our team at the University of Toronto's Acceleration Consortium. As a key member of our research team, you will play a critical role in advancing the field of AI-driven autonomous discovery and developing the materials and...