Senior Bioprocess Development Scientist

1 week ago

Toronto, Ontario, Canada Pyramid Consulting, Inc Full time

A challenging opportunity for a Senior Bioprocess Development Scientist is available in the Pharmaceutical Industry.

Salary: $35 - $40 per hour, with employee benefits including health insurance, 401(k) plan, and paid sick leave.

We are looking for a skilled professional to join our team at Pyramid Consulting, Inc. as a Biological Process Engineer.

Job Description:

The successful candidate will have experience in molecular cloning, protein expression, mammalian cell culture, and analytical techniques such as virus titration assays, FACS, protein assays, SDS-PAGE, Western blot, HPLC, and others.

Key Responsibilities:

  • Interphase with Global Antigen Design team to screen new vaccine candidates, design and improve various constructs through molecular engineering techniques, and perform genetic stability testing.
  • Collaborate with Upstream Scientists and lead a team of Technologists to plan and execute upstream process optimization and scale-up studies using technologies such as AMBR high-throughput bioreactor system, small and pilot-scale bioreactors.
  • Perform in-house or coordinate supportive analytical testing, including viral titration assays, FACS, SDS-PAGE, Western blot, HPLC, protein assays, and others.
  • Perform statistical data analysis, prepare technical reports, and stakeholder presentations.
  • Lead and/or contribute to characterization studies using Design of Experiments methodology.
  • Contribute to tech transfer of processes to Global Clinical manufacturing or Manufacturing Sciences and Technology.
  • Contribute to client's digital initiatives (e.g., AI).
  • Ensure compliance with client's GxP quality, documentation requirements, and HSE policies.

Requirements and Qualifications:

  • Education: PhD with 1+ years' experience or MSc with 3+ years' experience in Biochemical Engineering, Life Sciences, Biology, Immunology, or Biochemistry disciplines.
  • Skills:
    • Molecular cloning, protein expression, and mammalian cell culture.
    • Experience with analytical techniques such as virus titration assays, FACS, protein assays, SDS-PAGE, Western blot, HPLC, and others.
    • Hands-on experience in molecular engineering tools (molecular cloning, nucleic acid analysis, and protein expression).
    • Knowledge and experience with bioprocessing methods and process scale-up.
    • Mandatory computer skills: Word, Excel, PowerPoint.
    • Expertise in statistical analysis and software (JMP, GraphPad Prism) would be an asset.
    • Soft skills: leadership, organizational skills, accountability, motivation, attention to detail, analytical skills, communication, and interpersonal skills.
  • Language: English proficiency.

About Us: Pyramid Consulting, Inc. is a leading consulting firm providing equal employment opportunities to all employees and applicants for employment and prohibiting discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state, or local laws.

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