Post-doctoral Fellow

3 weeks ago

Toronto, Canada University Health Network Full time

**Job Posting #:923542**

**Site**:Princess Margaret Research Institute

**Department**:Cell and Molecular Biology**
**Reports to**:Principal Investigator**
**Hours: 37.5**

**Salary**:$25.10 - $31.38 hourly: To** commensurate with experience and consistent with UHN compensation policy**

**Status**:Temporary Full-time (1 Year; renewable)

**Posted Date: August 14,2023**

**Closing Date: Until Filled**

The University Health Network, where “above all else the needs of patients come first”, encompasses Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre, Toronto Rehabilitation Institute and the Michener Institute of Education. The breadth of research, the complexity of the cases treated, and the magnitude of its educational enterprise has made UHN a national and international resource for patient care, research and education. With a long tradition of ground breaking firsts and a purpose of “Transforming lives and communities through excellence in care, discovery and learning”, the University Health Network (UHN), Canada’s largest research teaching hospital, brings together over 16,000 employees, more than 1,200 physicians, 8,000+ students, and many volunteers. UHN is a caring, creative place where amazing people are amazing the world.

**Position Summary**

A POSTDOCTORAL position is available in the laboratory of Professor Hakem at the Princess Margaret Cancer Centre/University Health Network, Toronto/Canada.

Our research program focuses on identifying cancer genetic risk factors and characterization of cancer cell signaling pathways and molecular oncology mechanisms. Our team is committed to discover novel therapeutic strategies to improve the outcome of patients with aggressive cancer types.

Cancer genetics, biochemistry, epigenetics, chromatin remodeling, multiomics, and genome-wide CRISPR-Cas9 screening are the pillars of our research program. Our multidisciplinary studies also involve mouse models, Patients derived xenografts, Patient derived organoids as well as analysis of cancer databases (e.g., TCGA). Using systems biology, multidisciplinary approaches, and our strong collaborations with scientists, clinicians, pathologists, medicinal chemists, and computational biologists, we work towards our long-term goal “contributing to better diagnosis and therapy for cancer patients”.

The Hakem lab has excellent track records studying cancer mechanisms, and related signaling pathways. Our studies have been published in excellent peer-reviewed journals including Science (DOI: 10.1126/science.1094557), Nature Communications (DOI: 10.1038/ncomms12638), the Journal of Clinical Investigation (DOI: 10.1172/JCI140105 and DOI: 10.1172/JCI120401) and Nucleic Acids Research (DOI: 10.1093/nar/gkad172).

**Qualifications**
- PhD degree obtained within the past 2 to 3 years.
- Strong publication record.
- Highly self-motivated, and creative individual who can work effectively both independently and as a member of a team.
- Demonstrated excellent written and verbal communication skills.

Interested applicants should submit their CV, contact information of three referees (including their current and former supervisors), and a statement of research interests to Professor Hakem.

Applications will be reviewed on a rolling basis until the position is filled.

**Why join UHN?**

In addition to working alongside some of the most talented and inspiring healthcare professionals in the world, UHN offers a wide range of benefits, programs and perks. It is the comprehensiveness of these offerings that makes it a differentiating factor, allowing you to find value where it matters most to you, now and throughout your career at UHN.
- Competitive offer packages
- Close access to Transit and UHN shuttle service
- A flexible work environment
- Opportunities for development and promotions within a large organization
- Additional perks (multiple corporate discounts including: travel, restaurants, parking, phone plans, auto insurance discounts, on-site gyms, etc.)

Current UHN employees must have successfully completed their probationary period, have a good employee record along with satisfactory attendance in accordance with UHN's attendance management program, to be eligible for consideration.

Vaccines (COVID and others) are a requirement of the job unless you have an exemption on a medical ground pursuant to the Ontario Human Rights Code.

UHN is a respectful, caring, and inclusive workplace. We are committed to championing accessibility, diversity and equal opportunity. Requests for accommodation can be made at any stage of the recruitment process. Applicants need to make their requirements known in advance. Any information received related to an accommodation will be addressed confidentially.

University Health Network thanks all applicants, however, only those selected for an interview will be contacted.

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