Research Scientist
7 days ago
Research Scientist (Polymer & Bioconjugate Chemistry)
We are seeking a highly motivated Research Scientist (Polymer & Bioconjugate Chemistry) to join our exciting mass cytometry team based in Markham, ON.
Key Responsibilities- Work with minimal supervision to invent new reagents for mass cytometry.
- Review the literature and devise scientific plans.
- Synthesize reagents: Polymer synthesis and post-polymerization modifications; organic & inorganic synthesis.
- Characterize reagents by chemical analytical methods (e.g. GPC, NMR, etc.).
- Conjugate reagents to biomolecules such as antibodies.
- Use reagents and conjugated biomolecules to stain cells or tissue in bioanalytical assays (suspension or imaging mass cytometry); acquire, process, and interpret the bioanalytical data.
- Carry out all work with an eye towards making a practical, viable product.
- Document the feasibility of new reagents (invented by the candidate or by others) through written reports that include protocols, manufacturability considerations, and all other relevant information.
- Contribute to existing product scale-up and to addressing product performance issues.
- Be a point of contact for and collaborate with academic collaborators.
- Submit written invention disclosures to the IP department.
- Contribute original research and literature review presentations to group meetings.
- As needed, write and submit original research papers to peer-reviewed journals, and/or present posters and oral presentations at research conferences.
- Be the expert user and trainer for a few key pieces of laboratory equipment.
- Work with a cross-functional team of scientists and engineers from across all major fields.
- A PhD in chemistry or related field.
- Proven ability (in graduate school or industry) to incisively solve technical problems.
- Lead and complete projects.
- Experience with polymer synthesis and post-polymerization modification. Organic and inorganic synthesis is an asset.
- A variety of chemical and polymer characterization techniques.
- Chemical modification of biomolecules and the purification of the resultant bioconjugates.
- The use and care of complex analytical instrumentation, for example ICP-MS, HPLC.
- Flow cytometry, suspension mass cytometry, and/or imaging mass cytometry is an asset, but not required.
- Ability to read, interpret, and author technical procedures/protocols for laboratory equipment and experiments. General scientific writing and presentation skills.
- Familiarity with Design Control, ISO 13485, and/or regulatory environment is an asset.
- Excellent organizational and communication skills to enable multi-tasking in a fast-paced environment. Attention to detail is essential. Collaborative attitude and a team player.
- The ability to relocate to the Greater Toronto Area.
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