Senior Research Associate I, Protein Engineering
4 weeks ago
Key Responsibilities:
- Independently plan, perform, and optimize purification workflows of multispecific antibody therapeutics using AKTA (FPLC) systems, gravity flow columns, and high-throughput plate-based methods.
- Perform analytical and biophysical characterization of antibodies and other protein therapeutics for quality control, stability, and developability studies.
- Plan, execute, and evaluate binding studies using SPR, BLI, Kinexa, and/or flow cytometry methods, either independently or in collaboration with teammates.
- Analyze and review data, draw conclusions, and make recommendations for future investigations.
- Initiate and execute novel methods and/or suggest innovative and impactful changes to methods independently or in collaboration with team members.
- Participate in cross-departmental collaborative activities and present data at departmental and project team meetings.
- Seek to understand ongoing projects through attention to scientific literature, industry publications, and internally generated data and employ this understanding to improve contribution to project goals.
- Maintain a clean, organized, and operational lab.
- Conduct all activities in accordance with scientific standards, OH&S regulations, and established policies and practices.
- Actively work to foster an environment of effective and collaborative working relationships across the organization.
- Adhere to Zymeworks’ standard procedures for generating, documenting, and archiving data, maintaining an accurate, up-to-date electronic laboratory notebook.
Education and Experience:
Requires a MSc in a relevant scientific discipline with 3-5 years of relevant work experience, or equivalent combination of education and work experience.
Skills and Abilities:
- Good working knowledge and hands-on experience in several of the following areas: Protein purification (e.g. protein A/G/L, IEX, IMAC, and SEC) and familiarity with AKTA (FPLC) systems.
- Protein analytics: PAGE, CE-SDS, HPLC-SEC, cIEF, HIC, ELISA, DSC, DSF, DLS, MALS.
- Binding affinity measurements by SPR, BLI, or Kinexa.
- Additional experience with flow cytometry, FACS, or other fluorescence cell-based methods would be a plus.
- Experience with developability and stability assessments of antibody-based therapeutics would be desirable.
- Good organizational and time management skills, work effectively in a fast-paced, fast-changing environment.
- Good critical observation with analytical and problem-solving capabilities.
- Good communication skills, including scientific/technical writing and oral skills. Ability to present data effectively at team meetings and inter-departmental meetings.
Total Rewards:
We offer a comprehensive total rewards package, which includes competitive salaries, generous benefits, an outstanding work environment, and excellent opportunities for professional growth. The Canadian base salary range for this full-time position is $73,000 - $XX,000 + bonus + equity + benefits. Please note that the compensation details listed in role postings reflect the base salary only, and do not include bonus, equity, or benefits.
Our team enjoys:
- Industry-leading vacation and paid time off.
- Excellent health and wellness benefits.
- Zymelife health and wellness benefits.
- Paid time off to volunteer in your community.
- Matching country-specific pension savings program.
- Employee Share Purchase Program.
- Employee Equity Program.
All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin, or disability.
#J-18808-Ljbffr-
Vancouver, British Columbia, Canada Zymeworks Full timeJob SummaryZymeworks is seeking a highly skilled Senior Research Associate I, Protein Engineering to join our team. As a key member of our research team, you will be responsible for planning, executing, and optimizing protein purification workflows, as well as performing analytical and biophysical characterization of antibodies and other protein...
-
Vancouver, British Columbia, Canada Zymeworks Full timeJob SummaryZymeworks is seeking a highly skilled Senior Research Associate I, Protein Engineering to join our team. As a key member of our research team, you will be responsible for planning, executing, and optimizing protein purification workflows, as well as performing analytical and biophysical characterization of antibodies and other protein...
-
Vancouver, British Columbia, Canada Zymeworks Full timeKey ResponsibilitiesWe are seeking a highly skilled Senior Research Associate I, Protein Engineering to join our team at Zymeworks. The successful candidate will be responsible for independently planning, performing, and optimizing purification workflows of multispecific antibody therapeutics using AKTA (FPLC) systems, gravity flow columns, and...
-
Vancouver, British Columbia, Canada Zymeworks Full timeKey ResponsibilitiesWe are seeking a highly skilled Senior Research Associate I, Protein Engineering to join our team at Zymeworks. The successful candidate will be responsible for independently planning, performing, and optimizing purification workflows of multispecific antibody therapeutics using AKTA (FPLC) systems, gravity flow columns, and...
-
Vancouver, British Columbia, Canada Zymeworks Full timeJob SummaryWe are seeking a highly skilled and motivated Senior Research Associate I to join our Protein Engineering team at Zymeworks. The successful candidate will be responsible for independently planning, performing, and optimizing purification workflows of multispecific antibody therapeutics using AKTA (FPLC) systems, gravity flow columns, and...
-
Vancouver, British Columbia, Canada Zymeworks Full timeJob SummaryWe are seeking a highly skilled and motivated Senior Research Associate I to join our Protein Engineering team at Zymeworks. The successful candidate will be responsible for independently planning, performing, and optimizing purification workflows of multispecific antibody therapeutics using AKTA (FPLC) systems, gravity flow columns, and...
-
Protein Engineering Research Scientist
4 weeks ago
Vancouver, British Columbia, Canada AbCellera Full timeAbout AbCellera:AbCellera is at the forefront of revolutionizing drug development, focusing on antibody-based therapies that enhance patient outcomes. Our diverse team comprises scientists, engineers, and business professionals dedicated to advancing scientific knowledge and improving lives. We have pioneered technologies that unlock valuable drug targets,...
-
Protein Engineering Research Scientist
4 weeks ago
Vancouver, British Columbia, Canada AbCellera Full timeAbout AbCellera:AbCellera is a pioneering biotechnology firm dedicated to transforming the landscape of drug development, specifically in the realm of antibody-based therapies. Our diverse team, comprising scientists, engineers, and business professionals, is united by a shared vision: to enhance lives through scientific advancement. We have engineered...
-
Research Scientist
3 days ago
Vancouver, British Columbia, Canada AbCellera Full timeAbout the RoleWe are seeking a highly skilled Research Scientist to join our team at AbCellera, a global leader in antibody-based medicines. As a key member of our research team, you will play a critical role in implementing in-silico structural tools and processes in the areas of protein and antibody engineering.Key ResponsibilitiesDesign, implement, and...
-
Research Scientist
3 days ago
Vancouver, British Columbia, Canada AbCellera Full timeAbout the RoleWe are seeking a highly skilled Research Scientist to join our team at AbCellera, a global leader in antibody-based medicines. As a key member of our research team, you will play a critical role in implementing in-silico structural tools and processes in the areas of protein and antibody engineering.Key ResponsibilitiesDesign, implement, and...
-
Research Scientist
2 days ago
Vancouver, British Columbia, Canada AbCellera Full timeAbout the RoleWe are seeking a highly skilled Research Scientist to join our team at AbCellera, a global leader in antibody-based medicines. As a key member of our research team, you will play a critical role in implementing in-silico structural tools and processes in the areas of protein and antibody engineering.Key ResponsibilitiesDesign, implement, and...
-
Research Scientist
2 days ago
Vancouver, British Columbia, Canada AbCellera Full timeAbout the RoleWe are seeking a highly skilled Research Scientist to join our team at AbCellera, a global leader in antibody-based medicines. As a key member of our research team, you will play a critical role in implementing in-silico structural tools and processes in the areas of protein and antibody engineering.Key ResponsibilitiesDesign, implement, and...
-
Protein Engineering Research Scientist
4 weeks ago
Vancouver, British Columbia, Canada AbCellera Full timeAbout AbCellera:AbCellera is at the forefront of transforming drug development, focusing on antibody-based therapies that enhance patient outcomes. Our diverse team, comprising scientists, engineers, and business professionals, is dedicated to pushing the boundaries of science for the betterment of health.Position Overview:We are looking for a driven...
-
Protein Therapeutics Research Scientist
1 week ago
Vancouver, British Columbia, Canada Zymeworks Full timeJob SummaryWe are seeking a highly skilled and motivated Senior Research Associate I to join our Protein Engineering team at Zymeworks. As a key member of our team, you will be responsible for planning, executing, and optimizing purification workflows of multispecific antibody therapeutics.Key ResponsibilitiesIndependently plan, perform, and optimize...
-
Protein Therapeutics Research Scientist
1 week ago
Vancouver, British Columbia, Canada Zymeworks Full timeJob SummaryWe are seeking a highly skilled and motivated Senior Research Associate I to join our Protein Engineering team at Zymeworks. As a key member of our team, you will be responsible for planning, executing, and optimizing purification workflows of multispecific antibody therapeutics.Key ResponsibilitiesIndependently plan, perform, and optimize...
-
Senior Research Associate I, Protein Engineering
3 weeks ago
Vancouver, Canada Zymeworks Full timeKey Responsibilities: Independently plan, perform, and optimize purification workflows of multispecific antibody therapeutics using AKTA (FPLC) systems, gravity flow columns, and high-throughput plate-based methods. Perform analytical and biophysical characterization of antibodies and other protein therapeutics for quality control, stability, and...
-
Research Associate-protein Biochemistry
3 months ago
Vancouver, Canada Abdera Therapeutics Full time**Who we are** Abdera Therapeutics Inc. is a precision oncology company developing next-generation targeted radiation therapies - one of the most cutting-edge and highly promising areas of drug development. The company is built on a proprietary modular technology platform optimized for the delivery of radioisotopes to selectively destroy tumor cells while...
-
Senior Research Associate I, Protein Engineering
4 months ago
Vancouver, Canada Zymeworks Full timeKey Responsibilities Independently plan, perform, and optimize purification workflows of multispecific antibody therapeutics using AKTA (FPLC) systems, gravity flow columns, and high-throughput plate-based methods Perform analytical and biophysical characterization of antibodies and other protein therapeutics for quality control, stability, and...
-
Vancouver, British Columbia, Canada AbCellera Full timeAbout the RoleAbCellera is seeking a highly motivated and experienced Research Scientist to join our multidisciplinary team. As a key member of our research team, you will be responsible for designing, planning, and executing experiments to characterize antibodies and other therapeutic proteins using mass spectrometry and other analytical techniques.Key...
-
Vancouver, British Columbia, Canada AbCellera Full timeAbout the RoleAbCellera is seeking a highly motivated and experienced Research Scientist to join our multidisciplinary team. As a key member of our research team, you will be responsible for designing, planning, and executing experiments to characterize antibodies and other therapeutic proteins using mass spectrometry and other analytical techniques.Key...
