Senior Research Associate I, Protein Engineering

6 months ago

Vancouver, Canada Zymeworks Full time

Key Responsibilities

Independently plan, perform, and optimize purification workflows of multispecific antibody therapeutics using AKTA (FPLC) systems, gravity flow columns, and high-throughput plate-based methods Perform analytical and biophysical characterization of antibodies and other protein therapeutics for quality control, stability, and developability studies. Plan, execute, and evaluate binding studies using SPR, BLI, Kinexa and/or flow cytometry methods, either independently or in collaboration with teammates Analyze and review data, draw conclusions, and make recommendations for future investigations Initiate and execute novel methods and/or suggest innovative and impactful changes to methods independently or in collaboration with team members Participate in cross-departmental collaborative activities and present data at departmental and project team meetings Seek to understand ongoing projects through attention to scientific literature, industry publications, and internally generated data and employs this understanding to improve contribution to project goals Maintain a clean, organized, and operational lab Conduct all activities in accordance with scientific standards, OH&S regulations and established policies and practices Actively work to foster an environment of effective and collaborative working relationships across the organization Adhere to Zymeworks’ standard procedures for generating, documenting, and archiving data, maintaining an accurate, up-to-date electronic laboratory notebook

Education and Experience

Requires a MSc in a relevant scientific discipline with 3-5 years of relevant work experience, or equivalent combination of education and work experience

Skills and Abilities:

Good working knowledge and hands-on experience in several of the following areas: Protein purification (e.g. protein A/G/L, IEX, IMAC, and SEC) and familiarity with AKTA (FPLC) systems Protein analytics: PAGE, CE-SDS, HPLC-SEC, cIEF, HIC, ELISA, DSC, DSF, DLS, MALS Binding affinity measurements by SPR, BLI, or Kinexa Additional experience with flow-cytometry, FACS, or other fluorescence cell-based methods would be a plus Experience with developability and stability assessments of antibody-based therapeutics would be desirable Good organizational and time management skills, work effectively in a fast paced, fast changing environment Good critical observation with analytical and problem-solving capabilities Good communication skills, including scientific/technical writing and oral skills. Ability to present data effectively at team meetings and inter-departmental meetings
Total Rewards We offer a comprehensive total rewards package, which includes competitive salaries, generous benefits, an outstanding work environment, and excellent opportunities for professional growth. We regularly benchmark our compensation against leading biotechnology companies in our geographies. The Canadian base salary range for this full time position is $73, - $, + bonus + equity + benefits. Our salary ranges are determined by role, level, and location.
The range displayed on each job posting reflects the minimum and maximum target for new hire salaries for the position across all Canadian locations. Within the range, individual pay is determined by a variety of factors and the salary offered may vary depending on the successful candidate’s location and qualifications (including, but not limited to, job-related knowledge, education, training, skills, and experience). Please note that the compensation details listed in role postings reflect the base salary only, and do not include bonus, equity, or benefits. Our team enjoys: Industry leading vacation and paid time off Excellent health and wellness benefits Zymelife health and wellness benefits Paid time off to volunteer in your community Matching country specific pension savings program Employee Share Purchase Program Employee Equity Program All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin or disability.

  • Research Scientist

    4 weeks ago

    Vancouver, British Columbia, Canada AbCellera Full time

    Role Summary:AbCellera is seeking a highly skilled Research Scientist to join our team, focusing on in-silico protein engineering and structure design. As a key member of our research team, you will contribute to the development of innovative protein-based therapies, leveraging advanced computational tools and software suites, such as Rosetta.Key...

  • Senior Protein Engineer

    1 month ago

    Vancouver, British Columbia, Canada AbCellera Full time

    About the Role:We are seeking a highly motivated Research Scientist to execute and implement sequence and structure-based in-silico tools and workflows in the areas of protein and antibody engineering.You will interact with a diverse team, liaising between protein engineers, data scientists, software engineers, and wet-lab scientists, in a fast-paced...

  • Research Associate-protein Biochemistry

    6 months ago

    Vancouver, Canada Abdera Therapeutics Full time

    **Who we are** Abdera Therapeutics Inc. is a precision oncology company developing next-generation targeted radiation therapies - one of the most cutting-edge and highly promising areas of drug development. The company is built on a proprietary modular technology platform optimized for the delivery of radioisotopes to selectively destroy tumor cells while...

  • Research Associate I, Bioconjugation

    4 months ago

    Vancouver, Canada Zymeworks Full time

    Job Req ID: 1263- Location: Vancouver, BC, CAN- Additional Locations: N/A- Department: Bioconjugation- Job Type: Full Time- Workplace Type: On-Site**Research Associate I, Bioconjugation**: **Company Description** **Why Work With Us** Nothing is more critical to our success than the quality of our team. The work we do is meaningful and impactful - we care...

  • Research Associate II, Protein Engineering

    6 months ago

    Vancouver, Canada Zymeworks Full time

    Key Responsibilities Plans, performs, and optimizes purification workflows of multispecific antibody therapeutics using AKTA systems, gravity flow columns, and high-throughput plate-based methods. Provides analytical and biophysical characterization of antibodies and other protein therapeutics, including designing, planning, and executing...

  • Research Associate-protein Biochemistry

    6 months ago

    Vancouver, Canada Abdera Therapeutics Full time

    **Who we are** Abdera Therapeutics Inc. is a precision oncology company developing next-generation targeted radiation therapies - one of the most cutting-edge and highly promising areas of drug development. The company is built on a proprietary modular technology platform optimized for the delivery of radioisotopes to selectively destroy tumor cells while...

  • Protein Mass Spectrometry Research Scientist Opportunity

    4 weeks ago

    Vancouver, British Columbia, Canada AbCellera Full time

    At AbCellera, we're breaking the barriers of conventional drug development to propel antibody-based medicines from target to clinic.We're a team of scientists, engineers, creatives, and business professionals who believe that advancing science enhances lives. Our innovative technologies unlock high-value drug targets, including antibody-drug conjugates and...

  • Senior Antibody Bioinformatics Engineer

    3 weeks ago

    Vancouver, British Columbia, Canada AbCellera Full time

    At AbCellera, we are breaking the barriers of conventional drug development to propel antibody-based medicines from target to clinic. Our team of scientists, engineers, creatives, and business professionals believe that advancing science enhances lives.About UsWe have developed technologies to unlock high-value drug targets, including antibody-drug...

  • Protein Scientist, Biology

    2 months ago

    Vancouver, Canada Borealis Biosciences, Inc. Full time

    **Company**: Chronic kidney diseases are a severe and growing worldwide health challenge that affects 1 in 7 people. Without effective treatments patients can experience kidney failure leading to dialysis and transplantation, a high burden to patients, families and the health care system. Despite recent advances for certain kidney disease patients, many...

  • Research Associate

    1 month ago

    Vancouver, Canada University of British Columbia Full time

    Academic Job Category Faculty Non Bargaining Job Title Research Associate Department Subramaniam Laboratory | Department of Biochemistry and Molecular Biology | Faculty of Medicine (Sriram Subramaniam) Posting End Date December 8, 2024 Note: Applications will be accepted until 11:59 PM on the Posting End Date. Job End Date Dec 14, 2025 The...

  • Lead Protein Scientist for Antibody Discovery

    3 weeks ago

    Vancouver, British Columbia, Canada AbCellera Full time

    Antibody Discovery at AbCelleraAbCellera is a global leader in discovering and developing antibody-based medicines that improve people's lives. We are looking for a skilled Lead Protein Scientist to join our team.About the RoleWe are seeking an experienced Research Scientist with a strong background in biophysics to lead our protein science efforts in...

  • Biophysics Research Specialist

    3 weeks ago

    Vancouver, British Columbia, Canada AbCellera Full time

    About the OpportunityAbCellera is a global biotech company that discovers and develops antibody-based medicines to help patients live longer, happier lives. We are seeking a highly motivated Biophysics Research Specialist to join our Binding team as a co-op or intern for an 8-month term.This position will provide exposure to real-world projects and the...

  • Highly Motivated Protein Mass Spectrometry Researcher

    4 weeks ago

    Vancouver, British Columbia, Canada AbCellera Full time

    At AbCellera, we're pushing the boundaries of conventional drug development to bring life-changing antibody-based medicines from target to clinic.We're a team of driven scientists, engineers, creatives, and business professionals who believe that advancing science enhances lives. With cutting-edge technologies, we unlock high-value drug targets, including...

  • Research Associate/associate Scientist

    6 months ago

    Vancouver, Canada Abdera Therapeutics Full time

    **Who we are** Abdera Therapeutics Inc. is a precision oncology company developing next-generation targeted radiation therapies - one of the most cutting-edge and highly promising areas of drug development. The company is built on a proprietary modular technology platform optimized for the delivery of radioisotopes to selectively destroy tumor cells while...

  • Protein Product Development Manager

    6 months ago

    Vancouver, Canada Centennial Foodservice Full time

    **About the company** Centennial Food Solutions is a leading provider of customized quality center-of-the-plate products in Western Canada. Our goal is simple: to connect our communities through great food and exceptional service. Our reputation as a dependable and flexible partner is why discerning restaurants, retailers, foodservice, and trading companies...

  • Research Associate in Evolutionary Biochemistry

    2 months ago

    Vancouver, Canada UBC Full time

    Academic Job Category Faculty Non Bargaining Job Title Research Associate in Evolutionary Biochemistry Department Research | Tokuriki | Michael Smith Laboratories | Faculty of Science (Nobuhiko Tokuriki (On Leave)) Posting End Date November 21, 2024 **Note**: Applications will be accepted until 11:59 PM on the Posting End Date. Job End Date Oct 28, 2027 The...

  • Unlocking the Potential of Protein Science and Beyond

    3 weeks ago

    Vancouver, British Columbia, Canada AbCellera Full time

    We are always interested in expanding our teams with top talent, focusing on critical areas such as Protein Science, Drug Development, Manufacturing, and Quality Control. Additionally, we seek talented individuals who can meaningfully contribute to our teams focused on Translational Biology, Engineering, Bioinformatics, Machine Learning, IT Infrastructure,...

  • Research Associate

    1 month ago

    Vancouver, Canada University of British Columbia Full time

    Academic Job Category Faculty Non Bargaining Job Profile Research Associate Job Title Research Associate Department Nasiopoulos | Department of Electrical and Computer Engineering | Faculty of Applied Science Compensation Range $1.00 - $500,000.00 CAD Monthly Posting End Date December 7, 2024 Note: Applications will be accepted until 11:59 PM on...

  • Research Associate

    2 days ago

    Vancouver, Canada University of British Columbia Full time

    Academic Job Category Faculty Non Bargaining Job Title Research Associate Department Beck | Department of Civil Engineering | Faculty of Applied Science (Sara Beck (On Leave)) Posting End Date January 11, 2025 Note: Applications will be accepted until 11:59 PM on the Posting End Date. Job End Date Jan 31, 2026 The salary is...

  • Research Associate

    1 month ago

    Vancouver, Canada UBC Full time

    Academic Job Category Faculty Non Bargaining Job Title Research Associate Department Nasiopoulos | Department of Electrical and Computer Engineering | Faculty of Applied Science (Panos Nasiopoulos) Posting End Date December 7, 2024 **Note**: Applications will be accepted until 11:59 PM on the Posting End Date. Job End Date Dec 8, 2025 This position is...