Cancer Drug Development Expert
5 days ago
Unlocking high-value drug targets and pushing the boundaries of conventional drug development is at the heart of AbCellera's mission. As a global leader in antibody-based medicines, we're committed to propelling therapies from target to clinic with unprecedented speed and accuracy.
We're seeking an accomplished Cancer Drug Development Expert to join our team of scientists, engineers, and creatives who are passionate about advancing science for a better world. You'll play a key role in contributing to the assessment and development of antibody-based oncology drug candidates, ensuring seamless transition to human trials.
Your Key Responsibilities:
- Lead internal preclinical in vivo oncology models to support oncology programs
- Design and execute pharmacology studies to generate in vivo proof-of-concept and build confidence in selection of molecules for clinical development
- Collaborate with cross-functional teams, including biology, protein engineering, and pharmacokinetics scientists, as well as external CROs and collaborators, to optimize PK/PD studies and identify lead molecules
- Mentor team members in laboratory techniques related to tumour xenograft models
- Present findings to internal program teams and partners to inform data-driven decisions
- Evaluate preclinical and clinical data sets to develop testable biological hypotheses for oncology targets and assess those hypotheses preclinically
- Develop and oversee supporting assays to evaluate target modulation and downstream effects at the cellular, protein, and gene level
You'll be a great fit if you have:
- 10+ years of hands-on experience in oncology, immuno-oncology, and biologics drug development
- A PhD in Pharmacology, Immunology, or a related field, plus 10+ years of experience in a biopharmaceutical industry setting; MSc with 15 years of relevant experience will also be considered
- Proven interpersonal skills and ability to create value on cross-functional teams
- Genuine curiosity and interest in discussing innovative ideas in a fast-paced environment
- Effective communication skills to convey scientific and technical concepts with emphasis on application
- Ability to independently identify project needs and implement solutions
We offer:
A competitive salary range of CAD $141,600 - $177,000 annually, commensurate with your education and job-related knowledge, skills, and experience. In addition, you'll receive equity, annual bonus dependent on team and company performance, and a 6% (non-match) RRSP contribution. Other benefits include a CAD $1,500 annual Active Lifestyle Allowance, annual vacation, professional development opportunities, and comprehensive health benefits.
About AbCellera:
AbCellera is a pioneering biotech company that discovers and develops antibody-based medicines to help people live longer, happier, and more productive lives. We're driven by a passion for innovation and a commitment to bringing better therapies to patients. Our team is dedicated to pushing the limits of science and technology to achieve this vision.
To succeed in this role, you should possess:
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