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Clinical Pharmacokinetics Specialist

2 months ago

Vancouver, British Columbia, Canada Zymeworks Full time
Key Responsibilities

We are seeking a highly skilled Clinical Pharmacokinetics Specialist to join our team at Zymeworks. As a key member of our Clinical Pharmacology group, you will be responsible for utilizing advanced analytic software to integrate PK drug concentration-time measures, pharmacodynamic responses, and clinical safety and efficacy information for PK/PD and Modeling and Simulation (M&S) analyses.

Responsibilities:
  • Represent Clinical Pharmacology line function and work collaboratively with cross-functional teams to support late-stage discovery programs from preclinical development to IND filing and throughout clinical development.
  • Analyze, interpret, and report clinical PK data as a member of multidisciplinary development program teams.
  • Work with clinical teams to design PK components in various study designs, such as first-in-human and drug-drug interaction studies.
  • Maintain a working knowledge of pharmacology, biology, therapeutics, drug metabolism, bioanalysis, and biopharmaceutics.
  • Develop and maintain relationships with internal and external clients and scientists.
  • Review and author scientific publications, abstracts, and posters.
  • Present results to supervisors and project teams in a logical and clear manner.
  • Work closely with SAS programmers and Clinical Operations to ensure timely delivery of results.
Qualifications and Experience

To be successful in this role, you will require:

  • A PhD or equivalent in Pharmacology/Biomedicine/Biochemistry or a related scientific discipline.
  • Minimum 3-5 years of relevant experience within a pharmaceutical industry, contract research, or clinical research.
  • Solid PK training and experience.
  • Experience with clinical development of therapeutic molecules is highly desirable.
  • Proficiency in Phoenix WinNonlin for non-compartmental analysis.
  • Hands-on experience with clinical pharmacology-related work, including regulatory and scientific documentation writing.
  • Advanced spreadsheet skills are desirable.
  • Familiarity with PK, ADA, and NAb bioanalytical methods development and validation is an asset.
Total Rewards

We offer a comprehensive total rewards package, including:

  • Competitive salaries.
  • Generous benefits.
  • An outstanding work environment.
  • Excellent opportunities for professional growth.

Our salary ranges are determined by role, level, and location. The Canadian base salary range for this full-time position is $94,000 - $, + bonus + equity + benefits. Our team enjoys:

  • Industry-leading vacation and paid time off.
  • Excellent health and wellness benefits.
  • Matching country-specific pension savings program.
  • Employee Share Purchase Program.
  • Employee Equity Program.

Zymeworks is an equal opportunities employer and welcomes applications from diverse candidates. We are committed to creating an inclusive work environment that values diversity and promotes equal opportunities for all employees and job applicants.