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Senior Biopharmaceutical Researcher
2 months ago
About the Role
We are seeking a highly motivated Research Scientist with a strong background in bioanalytical methods for antibodies or proteins, to join our multidisciplinary Pharmacokinetics team at AbCellera. As a member of our team, you will be based in the lab and have a great opportunity to help build out pharm-tox capabilities supporting lead antibody identification and progression into the clinic.
Your Key Responsibilities
- Designing & running in vivo pharmacokinetics studies across a diverse portfolio of antibody development programs
- Generating pharmacokinetic and pharmacodynamic data from biological samples to critically assess the promise of individual antibody programs
- Developing, qualifying and implementing ligand binding assays for PK, TK, ADA and PD support in various species and biological matrices
- Liaising with external CROs to execute in vivo studies, and for generation and characterization of assay critical reagents
- Collaborating with teams across the company to solve problems, analyze, interpret and communicate data
- Training and mentoring more junior scientists
- Growing your technical skill set and engaging in professional development
- Preparing and authoring materials to educate colleagues as well as communicate strategies, key findings and implications
Your Qualifications
- You have experience with pharmacokinetics analysis and interpretation, ideally in an industry setting, and are excited about the opportunity to learn and apply new lab techniques in a drug development setting
- You have a PhD in a relevant field, or a MSc with at least 5 years work experience in an industrial or academic wet lab environment
- You have experience running pharmacokinetic studies and analyzing pharmacokinetic data, and have a strong understanding of antibody structure and function
- You have experience with non-compartmental and compartmental data analysis, and demonstrated expertise with assay qualification and process optimization
- You have exceptional analytical and problem-solving capabilities, as well as excellent documentation, organizational, and communication skills
- You have proven interpersonal skills with the ability to work collaboratively as a member of a cross-functional team
- You have experience working with LC-MS for the quantification of large molecules in biological samples (desirable)
What We Offer
We offer a competitive salary range of $75,000 - $95,000 annually, commensurate with your education and job-related knowledge, skills, and experience. You will also receive equity, annual bonus dependent on team and company performance, and 6% (non-match) RRSP contribution. In addition, you will have a $1,500 annual Active Lifestyle Allowance, annual vacation, professional development opportunities, and comprehensive health benefits.
About AbCellera
AbCellera is a global company that discovers and develops antibody-based medicines that help people live longer, happier, and more productive lives. We are focused on bringing innovative medicines to patients, both by advancing our internal pipeline of programs and partnering with companies that have novel science or innovative technology.
