Scientist, Bioconjugation Chemistry

3 weeks ago


Vancouver, Canada Synectics Inc. Full time
We are seeking a skilled and collaborative scientist with expertise in bioconjugation chemistry to join our chemistry group. This exciting role involves designing, synthesizing, and analyzing protein-oligonucleotide conjugates, including antibodies, antibody fragments, and other target-binding scaffolds. The ideal candidate will have experience in protein biochemistry, bioconjugation, bioconjugate purification, and oligonucleotide therapeutics. This is a fantastic opportunity to work in an innovative biotech environment focused on RNA medicines for kidney disease.

Education And Experience

  • Ph.D. in Chemistry, Protein Biochemistry, or a related science discipline with a focus on bioconjugation chemistry and 1+ year of industry experience; or M.Sc. with 5+ years of relevant experience.
  • Strong foundation in bioconjugation, analytical chemistry, and/or chemical biology.
  • Experience with HPLC purification and analytical methods for proteins and oligonucleotides.
  • Proficiency in bioconjugation strategies for proteins, peptides, lipids, and oligonucleotides.
  • Expertise in bioconjugate purification techniques, including liquid chromatography methods (RP, IEX, SEC, HIC, FPLC) and membrane filtration methods (e.g., TFF).
  • Familiarity with biochemistry techniques and analytical tools like SEC-MALs, LCMS, SPR/BLI, ELISA, and SDS-PAGE.



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