Clinical Research Scientist I

2 days ago

Vancouver, Canada Xenon Pharmaceuticals Inc. Full time
h3>Research Scientist 1/Research Scientist 2, Chemistry

Tuesday, December 10, 2024

Who We Are:

Xenon Pharmaceuticals (NASDAQ:p>

What We Do:

We are advancing an exciting product pipeline to address indications with high unmet medical need, including epilepsy and depression. Our flagship azetukalner program represents the most advanced potassium channel modulator in clinical development for multiple indications. Building upon the positive results and compelling data from our Phase 2b “X-TOLE” study in adult patients with focal epilepsy, our Phase 3 epilepsy program includes multiple clinical trials evaluating azetukalner in patients with focal onset seizures and primary generalized tonic-clonic seizures. In 2024, we are planning to initiate a Phase 3 azetukalner program in major depressive disorder, based on topline data from our Phase 2 “X-NOVA” clinical trial. In addition, we are proud of the leading-edge science coming out of our discovery labs, including early-stage research programs that leverage our extensive ion channel expertise and drug discovery capabilities to identify validated drug targets and develop new product candidates. Backed by a strong balance sheet to support our growth plans, we continue to build a fully integrated, premier neuroscience company with strong discovery, clinical development, corporate, and commercial operations.

About the Role:

We are seeking a Research Scientist 1/ Research Scientist 2, Chemistry to join our Chemistry team for a 12 month fixed-term contract position. This individual will contribute to Xenon’s drug discovery programs by applying synthetic and medicinal chemistry skills. This individual possesses the ability to design and implement basic medicinal chemistry targets and will independently execute the synthesis, purification, and characterization of these targets. The Research Scientist 1/ Research Scientist 2, Chemistry will also utilize novel synthetic technologies for targets and engage with cross-functional scientists, presenting results at both internal and external meetings in a clear and precise manner.

This position reports to the Senior Research Scientist, Chemistry and will be in Vancouver, BC, Canada. strong>

  • Effectively design drug candidates that advance SAR based on analysis of biological, DMPK, and physicochemical properties data.
  • Analyze data, interpret results and recommend appropriate action.
  • Utilize essential tools of computational chemistry for hypothesis-driven medicinal chemistry.
  • Demonstrate leadership in keeping abreast of scientific developments, patents, and medicinal chemistry literature.
  • Prepare technical reports, SOPs, patent procedures, summaries, and quantitative analyses.
  • Prepare presentation materials and clearly communicate research results at internal and external meetings.
  • Work closely with project team and chemistry leads to generate and implement design, strategy, and execution of medchem strategies as well as coordination with intellectual property and other functions when necessary.
  • Maintain a detailed laboratory notebook according to corporate standards and SOPs and ensure the same for direct reports.
  • Keep laboratory environment safe and well-organized.
  • Keep up to date and detailed records of experiments and data analysis within an Electronic Lab Notebook system. li>
  • Ensure the laboratory environment is safe and well-organized; follow and keep up to date with Health & Safety policies.
  • Act in accordance with Company policies, including, for example, the Code of Business Conduct and Ethics and ensure policies are understood and followed by direct reports, if any.

QUALIFICATIONS:

  • MSc degree with 4+ years of experience or PhD degree with 2+ years of experience in chemistry.
  • Ability to draw on literature and utilize computational chemistry tools to generate hypothesis-driven medicinal chemistry targets.
  • Track record of working in a cross-functional environment in a flexible manner.

The base salary range for this role is $76,139 to $101,354 CAD; p>

Our Total Rewards program includes base salary, target bonus, and stock options, as well as a full range of benefits including medical, dental, vision, short- & long-term disability, accidental death & dismemberment, and life insurance programs, Employee Assistance Program, travel insurance, and retirement savings programs with company matching contributions.

  • Clinical Research Scientist I

    3 weeks ago

    Vancouver, Canada Stein's Garden & Home Full time

    h3>Research Scientist 1/Research Scientist 2, ChemistryTuesday, December 10, 2024Who We Are:Xenon Pharmaceuticals (NASDAQ:p>What We Do:We are advancing an exciting product pipeline to address indications with high unmet medical need, including epilepsy and depression. Our flagship azetukalner program represents the most advanced potassium channel modulator...

  • Clinical Research Scientist I

    2 days ago

    Vancouver, Canada Xenon Pharmaceuticals Inc. Full time

    p>We are advancing an exciting product pipeline to address indications with high unmet medical need, including epilepsy and depression. Our flagship azetukalner program represents the most advanced potassium channel modulator in clinical development for multiple indications. Building upon the positive results and compelling data from our Phase 2b...

  • Clinical Research Scientist I

    4 weeks ago

    Vancouver, Canada The Gear Centre Group Full time

    p>What We Do:We are advancing an exciting product pipeline to address indications with high unmet medical need, including epilepsy and depression. Our flagship azetukalner program represents the most advanced potassium channel modulator in clinical development for multiple indications. Building upon the positive results and compelling data from our Phase 2b...

  • Clinical Research Scientist I

    4 weeks ago

    Vancouver, Canada The Gear Centre Group Full time

    p>What We Do:We are advancing an exciting product pipeline to address indications with high unmet medical need, including epilepsy and depression. Our flagship azetukalner program represents the most advanced potassium channel modulator in clinical development for multiple indications. Building upon the positive results and compelling data from our Phase 2b...

  • Associate Research Scientist

    3 weeks ago

    Vancouver, Canada Alpha 9 Oncology Full time

    Marie CurieWe are seeking driven, creative, and entrepreneurial individuals to help shape our company. We are passionate about developing new medicines to help people living with cancer, and we are looking to add to our growing team.Our Core ValuesDeliver On Our MissionWe are:InnovativeDrivenAgileTenaciousElevate Our PeopleWe...

  • Operations Research Scientist

    7 months ago

    Vancouver, Canada Providence Healthcare Full time

    Article Flag: Mandatory Vaccination Please Note: As per the current Public Health Orders (Long Term Care/Seniors Assisted Living Provincial Health Order and the Health Sector Order), as of October 26, 2021, all employees working for Providence Health Care must be fully vaccinated against COVID-19. Proof of vaccination status will be required. Reporting to...

  • Operations Research Scientist

    7 months ago

    Vancouver, Canada Providence Healthcare Full time

    Article Flag: Mandatory Vaccination Please Note: As per the current Public Health Orders (Long Term Care/Seniors Assisted Living Provincial Health Order and the Health Sector Order), as of October 26, 2021, all employees working for Providence Health Care must be fully vaccinated against COVID-19. Proof of vaccination status will be...

  • Clinical Research Coordinator

    7 months ago

    Vancouver, Canada Providence Research Full time

    **Organization**:Vancouver Costal Cardiac Surgery Research Group **Location**: St. Paul’s Hospital, Division of Cardiac Surgery **Hours**: Full-Time, In-Person The Vancouver Costal Cardiac Surgery Research Group specializes in investigator-driven and industry sponsored clinical trials and studies covering a wide range of surgical devices, techniques and...

  • Clinical Scientist

    1 week ago

    Vancouver, Canada Labcorp Full time

    **Clinical Scientist Support, FSP, Oncology** **Remote - Canada** **This is a role that involves supporting medical monitoring. This is not a laboratory scientist role.** As a leading contract research organization (CRO), Labcorp Drug Development provides comprehensive drug development solutions for a range of industries. Our services cover the...

  • Clinical Research Associate Oncology Specialist

    3 weeks ago

    Vancouver, British Columbia, Canada i-Pharm Consulting Full time

    Job SummaryWe are seeking a highly skilled Clinical Research Associate (CRA) II to join our team at i-Pharm Consulting, supporting cutting-edge oncology clinical trials. The successful candidate will oversee and manage the progress of clinical trials at investigational sites, ensuring adherence to study protocols, ICH-GCP, and local regulatory...

  • Bioinformatics Scientist

    3 months ago

    Vancouver, Canada University of British Columbia Full time

    Staff - Non Union Job Category M&P - AAPS Job Profile AAPS Salaried - Statistical Analysis, Level A Job Title Bioinformatics Scientist Department Research I Marra I Michael Smith Laboratories I Faculty of Science Compensation Range $6,251.00 - $8,986.00 CAD Monthly The Compensation Range is the span between the minimum and maximum base salary for...

  • Research Scientist, Biology

    4 days ago

    Vancouver, Canada Xenon Pharmaceuticals Inc. Full time

    **Who We Are**: **At Xenon Pharmaceuticals (NASDAQ**: XENE), we are committed to providing a brighter future for patients suffering from neurological disorders. Our employees are smart, passionate, dedicated, and driven by their incredibly important work to discover, develop, and deliver innovative medicines for patients in need. We are looking for great...

  • Clinical Research Coordinator

    7 months ago

    Vancouver, Canada Providence Research Full time

    **Job summary** This position receives direction from the clinical research manager and principal investigators. This position receives direction on financial and budgetary tasks and requirements from the research accountant. The coordinator is required to exercise initiative and judgment in establishing priorities and carrying tasks through to...

  • Clinical Research Coordinator

    2 weeks ago

    Vancouver, Canada Black Tusk Research Group Full time

    **JOB TITLE** Clinical Research Coordinator Full-Time, permanent Onsite - Downtown Vancouver **Wage -**$20-$25/hr **REPORTS TO** The Clinical Research Coordinator will report to the Clinical Research Manager. **COMPANY OVERVIEW** Black Tusk Research Group is a Site Management Organization (SMO) located in downtown Vancouver that specializes in...

  • Clinical Research Coordinator

    7 months ago

    Vancouver, Canada Black Tusk Research Group Full time

    **JOB TITLE** Clinical Research Coordinator Full-Time, permanent Onsite - Downtown Vancouver **Wage - **$20-$25/hr **REPORTS TO** The Clinical Research Coordinator will report to the Clinical Research Manager. **COMPANY OVERVIEW** Black Tusk Research Group is a Site Management Organization (SMO) located in downtown Vancouver that specializes in...

  • Biomedical Research Coordinator

    3 weeks ago

    Vancouver, British Columbia, Canada i-Pharm Consulting Full time

    About i-Pharm ConsultingWe are a global leader in healthcare data, technology, and advanced analytics, dedicated to supporting the pharmaceutical and biotechnology industries in the development of groundbreaking treatments. With a strong focus on oncology, our mission is to accelerate the discovery and development of life-changing therapies.Job OverviewAs an...

  • Research Scientist, Health Economics and Outcomes

    4 days ago

    Vancouver, Canada Broadstreet Health Economics and Outcomes Research Full time

    We are an independent consultancy in Vancouver British Columbia, specializing in epidemiology, evidence synthesis, and health economics, with a particular focus on creating customized solutions to best meet our clients’ diverse needs. Our team comprises epidemiologists, health economists, statisticians, and IT specialists. Our projects are led by senior...

  • Clinical Trials Specialist

    3 weeks ago

    Vancouver, British Columbia, Canada i-Pharm Consulting Full time

    Discover a challenging and rewarding career as a Clinical Trials Specialist with i-Pharm Consulting, a global leader in healthcare data, technology, and advanced analytics. We are seeking a highly skilled and experienced Clinical Research Associate II (CRA II) to join our team and contribute to the success of cutting-edge oncology clinical trials.About the...

  • Research Scientist

    2 months ago

    Vancouver, Canada Amazon Full time

    h3>Applied Scientist, Financial Insights and ActionsAre you interested in changing the way accounting and finance works at Amazon? We are a science and engineering team leveraging ML models and LLMs to solve real-world problems faced by accountants and financial analysts.We are part of the Amazon Financials Foundation Services (AFFS) organization. AFFS is...

  • Research Scientist

    1 month ago

    Vancouver, Canada Amazon Full time

    h3>Applied Scientist, Financial Insights and ActionsAre you interested in changing the way accounting and finance works at Amazon? We are a science and engineering team leveraging ML models and LLMs to solve real-world problems faced by accountants and financial analysts.We are part of the Amazon Financials Foundation Services (AFFS) organization. AFFS is...