Protein Scientist, Biology

3 months ago

Vancouver, Canada Borealis Biosciences, Inc. Full time

**Company**:
Chronic kidney diseases are a severe and growing worldwide health challenge that affects 1 in 7 people. Without effective treatments patients can experience kidney failure leading to dialysis and transplantation, a high burden to patients, families and the health care system. Despite recent advances for certain kidney disease patients, many forms of highly prevalent kidney diseases do not have effective treatments.

Borealis was founded on the premise that a convergence of scientific and translational breakthroughs will enable RNA therapeutics to address some of the largest untreated kidney diseases and beyond. Borealis builds on the success of Chinook Therapeutics, a kidney disease company with a research site in Vancouver that was acquired by Novartis in 2023 for up to $3.5 billion. The Borealis team has strong leadership and academic advisors who were central to research at Chinook, together with additional leadership in the field of RNA therapeutics. We are headquartered in Vancouver, BC, with state-of-the-art wet labs for molecular and cellular biology, in vivo pharmacology, chemistry, DMPK, bioinformatics and analytical capabilities.

**Position**:
**Responsibilities include**:

- Oversee antibody discovery campaign and support the design, generation, and screening of biologics of various formats
- Develop and perform biophysical and functional assays to profile lead compounds.
- Build internal capabilities for protein/drug-conjugate biophysical and functional characterization.
- Manage outsourcing for protein production and analysis with CROs.
- Actively communicate and present scientific findings in group discussions as well as inter-departmental and company-wide meetings.
- Collaborate and work with a diverse group of scientists across departments to ensure timely progress in research projects.

**Location**:

- This is an on-site lab-based position located in Borealis’ Vancouver, BC headquarters. Much of your time will be spent in conducting wet lab work.

**Education, Experience, and Skills**:

- PhD in Biochemistry, Biophysics, Molecular Biology or other relevant field with at least 1 year of directly related industry experience; MSc with minimum 5 years directly relevant industry experience, or other equivalent combination of education and experience.
- Expertise in protein/antibody design and engineering, with hands-on experience in biophysical and functional assays for characterization.
- Broad knowledge and/or experience in protein/antibody production, purification, and bioconjugation.
- Experience in CRO management or external collaboration.
- Good time management and communication skills.
- Fast learner, with great problem-solving skills to resolve potential issues that arise.
- Positive attitude and high personal and ethical standards.
- A strong team player with a passion for science and drug discovery.

**Compensation**:The annual salary range is $113,000 - $131,000 and Borealis Bio provides competitive benefits including RRSP matching, extended medical, dental, vision and a Wellness Spending Account up to $1,800 per year.
- Borealis is an Equal Opportunity Employer, and we prohibit discrimination or harassment of any kind. We are committed to fostering an environment where ALL people are welcome and supported. _We cultivate a culture of inclusion for all employees that respects their individual strengths, views, and experiences. We believe that our differences enable us to be a better team - one that makes better decisions, drives innovation, and delivers better business results. Creativity and innovation flourish in an environment of openness, inclusion, and mutual respect._

  • Lead Protein Scientist for Antibody Discovery

    4 weeks ago

    Vancouver, British Columbia, Canada AbCellera Full time

    Antibody Discovery at AbCelleraAbCellera is a global leader in discovering and developing antibody-based medicines that improve people's lives. We are looking for a skilled Lead Protein Scientist to join our team.About the RoleWe are seeking an experienced Research Scientist with a strong background in biophysics to lead our protein science efforts in...

  • Senior Protein Engineer

    1 month ago

    Vancouver, British Columbia, Canada AbCellera Full time

    About the Role:We are seeking a highly motivated Research Scientist to execute and implement sequence and structure-based in-silico tools and workflows in the areas of protein and antibody engineering.You will interact with a diverse team, liaising between protein engineers, data scientists, software engineers, and wet-lab scientists, in a fast-paced...

  • Associate Scientist, in Vitro Biology

    6 months ago

    Vancouver, Canada Zymeworks Full time

    Job Req ID: 1126- Location: Vancouver, BC, CAN- Additional Locations: N/A- Department: In Vitro Biology- Job Type: Full Time- Workplace Type: On-Site**Associate Scientist, In Vitro Biology**: **Company Description** **Why Work With Us** Nothing is more critical to our success than the quality of our team. The work we do is meaningful and impactful - we...

  • Scientist/Senior Scientist, Biology

    2 weeks ago

    Vancouver, Canada Alpha-9 Oncology Full time

    Scientist, Senior Scientist Biology About UsAlpha-9 Oncology is a clinical-stage biotechnology company developing radiopharmaceuticals for solid and hematologic malignancies. Alpha-9 has a portfolio of molecules entering clinical trials and a robust pipeline of additional targets for future development. With a strong cash position, raised from leading...

  • Senior Scientist, Cell Biology Specialist

    1 month ago

    Vancouver, British Columbia, Canada Zymeworks Full time

    At Zymeworks, we are committed to discovering and developing innovative cancer therapies. As a Senior Scientist, Cell Biology Specialist, you will play a crucial role in our team's success.Key ResponsibilitiesYou will oversee the design, coordination, execution, and analysis of in vitro pharmacology experiments for the screening and progression of novel...

  • Data Scientist in Biostatistics and Biology

    2 weeks ago

    Vancouver, British Columbia, Canada Botanical Society of America Full time

    Unlock Your Potential as a Data ScientistWe are seeking an exceptional Data Scientist in Biostatistics and Biology to join our esteemed faculty at the University of British Columbia.About the Role: As a tenure-track Assistant Professor of Teaching, you will be responsible for teaching biostatistics and biology courses, coordinating teaching teams, and...

  • Research Scientist

    2 months ago

    Vancouver, Canada AbCellera Biologics Full time

    AbCellera is breaking the barriers of conventional drug development to propel antibody-based medicines from target to clinic. We are a team of scientists, engineers, creatives, and business professionals who believe that advancing science enhances lives. We have developed technologies to unlock high-value drug targets, including antibody-drug conjugates and...

  • Research Scientist

    2 months ago

    Vancouver, Canada AbCellera Full time

    AbCellera is breaking the barriers of conventional drug development to propel antibody-based medicines from target to clinic. We are a team of scientists, engineers, creatives, and business professionals who believe that advancing science enhances lives. We have developed technologies to unlock high-value drug targets, including antibody-drug conjugates and...

  • Protein Therapeutics Specialist

    4 weeks ago

    Vancouver, British Columbia, Canada Zymeworks Full time

    About the RoleWe are seeking a highly skilled Protein Therapeutics Specialist to join our team at Zymeworks. In this role, you will be responsible for planning, performing, and optimizing purification workflows of multispecific antibody therapeutics using AKTA systems, gravity flow columns, and high-throughput plate-based methods.Key...

  • Molecular Biology and Antibody Expression Intern

    1 month ago

    Vancouver, Canada AbCellera Biologics Full time

    AbCellera is breaking the barriers of conventional drug development to propel antibody-based medicines from target to clinic. We are a team of scientists, engineers, creatives, and business professionals who believe that advancing science enhances lives. We have developed technologies to unlock high-value drug targets, including antibody-drug conjugates and...

  • Cancer Biology Research Scientist

    3 weeks ago

    Vancouver, British Columbia, Canada PHSA Full time

    Job Description:We are seeking a highly skilled Cancer Biology Research Scientist to join our team at the British Columbia Cancer Research Institute (BCCRI).The successful candidate will have a strong background in cancer biology and experience with developing or working with in vivo animal modeling of human solid tumors. They will also have a proven track...

  • Proteomics Research Scientist

    4 weeks ago

    Vancouver, British Columbia, Canada PHSA Full time

    About BC CancerAt BC Cancer, we're committed to reducing the incidence of cancer, reducing mortality from cancer, and improving the quality of life for those living with cancer. We provide a comprehensive cancer control program for the people of British Columbia by working with community partners to deliver a range of oncology services.We're seeking a...

  • Proteomics Research Scientist

    3 weeks ago

    Vancouver, British Columbia, Canada PHSA Full time

    We are seeking a highly skilled and motivated Proteomics Research Scientist to join our team at BC Cancer. As a key member of our research team, you will be responsible for developing an independent research program in biological mass spectrometry and proteomics for biomarker and target identification, or protein function analysis in cancer.The successful...

  • Senior Biophysics Scientist – Mass Spectrometry Expert

    4 weeks ago

    Vancouver, British Columbia, Canada AbCellera Full time

    Unlock the Secrets of Protein CharacterizationAbout AbCelleraAbCellera is a cutting-edge biotechnology company that develops innovative antibody-based medicines to improve patients' lives. Our mission is to advance science and technology to bring better therapies to those who need them most.Job DescriptionWe are seeking an experienced Senior Biophysics...

  • Senior Antibody Bioinformatics Engineer

    4 weeks ago

    Vancouver, British Columbia, Canada AbCellera Full time

    At AbCellera, we are breaking the barriers of conventional drug development to propel antibody-based medicines from target to clinic. Our team of scientists, engineers, creatives, and business professionals believe that advancing science enhances lives.About UsWe have developed technologies to unlock high-value drug targets, including antibody-drug...

  • Protein Engineering Intern

    1 month ago

    Vancouver, Canada AbCellera Full time

    AbCellera is breaking the barriers of conventional drug development to propel antibody-based medicines from target to clinic. We are a team of scientists, engineers, creatives, and business professionals who believe that advancing science enhances lives. We have developed technologies to unlock high-value drug targets, including antibody-drug conjugates and...

  • Cancer Biology Research Scientist Position in Vancouver BC

    4 weeks ago

    Vancouver, British Columbia, Canada PHSA Full time

    We are seeking a highly skilled Cancer Biology Research Scientist to join our team at the British Columbia Cancer Research Institute (BCCRI) in Vancouver, BC.The successful candidate will have proven expertise in cancer biology and a strong track record of research in tumour development, cell plasticity, and metastasis. They should also have experience with...

  • Principal Scientist

    6 months ago

    Vancouver, Canada AbCellera Full time

    AbCellera is a young, energetic, and rapidly growing tech company with an amazing team that searches, decodes, and analyzes natural immune systems to find antibodies that its partners can develop into drugs to prevent and treat disease. Our Translational Biology group is seeking an experienced and exceptional individual for the role of Principal Scientist -...

  • Principal Scientist

    6 months ago

    Vancouver, Canada AbCellera Biologics Full time

    AbCellera is a young, energetic, and rapidly growing tech company with an amazing team that searches, decodes, and analyzes natural immune systems to find antibodies that its partners can develop into drugs to prevent and treat disease. Our Translational Biology group is seeking an experienced and exceptional individual for the role of Principal Scientist -...

  • Principal Scientist

    6 months ago

    Vancouver, Canada AbCellera Biologics Full time

    AbCellera is breaking the barriers of conventional drug development to propel antibody-based medicines from target to clinic. We are a team of scientists, engineers, creatives, and business professionals who believe that advancing science enhances lives. We have developed technologies to unlock high-value drug targets, including antibody-drug conjugates and...