Lead Oncology Research Scientist

1 day ago


Vancouver, British Columbia, Canada AbCellera Full time

About AbCellera

AbCellera is a team of scientists, engineers, creatives, and business professionals who believe that advancing science enhances lives. We have developed technologies to unlock high-value drug targets.

About the Role

We are looking for a highly motivated Lead Oncology Research Scientist with a strong oncology and immunology background to join our team. This scientist will contribute to the assessment and development of antibody-based oncology drug candidates. The position involves internal R&D as well as external collaborative research.

Main Responsibilities

  • Leading preclinical in vivo oncology models to support oncology programs
  • Designing, supporting, and interpreting pharmacology studies to generate in vivo proof-of-concept and build confidence in selection of molecules for clinical development
  • Collaborating with in vitro biology, protein engineering, and pharmacokinetics scientists, as well as external CROs and collaborators, to execute efficient PK/PD studies to identify lead molecules and advance programs to human trials
  • Mentoring team members in laboratory techniques related to tumour xenograft models
  • Reporting findings to internal program teams and partners to support data-driven decisions
  • Evaluating available preclinical and clinical data sets to build testable biological hypotheses for oncology targets and then preclinically assessing those hypotheses
  • Developing and overseeing supporting assays to assess target modulation and downstream effects at the cellular, protein, and gene level

Requirements

  • 10+ years of hands-on experience in oncology, immuno-oncology, and biologics drug development
  • A PhD in pharmacology, immunology, or related field, plus 10+ years of experience in a biopharmaceutical industry setting; or a MSc and 15 years of relevant experience
  • Proven interpersonal skills and ability to create value on cross-functional teams
  • Genuine curiosity, with an interest in discussing innovative ideas in a highly collaborative and fast-paced environment
  • Ability to communicate scientific and/or technical concepts with an emphasis on application
  • Independence in identifying project needs and implementing solutions
  • Enjoyment of teamwork in solving complicated biological questions and building data sets that help to predict the success of therapies

What We Offer

  • A competitive salary range of CAD $141,600 - $177,000 annually, commensurate with your education and job-related knowledge, skills, and experience
  • Equity and annual bonus dependent on team and company performance
  • A 6% (non-match) RRSP contribution
  • A CAD $1,500 annual Active Lifestyle Allowance
  • Annual vacation, opportunity for flexible work arrangements, professional development opportunities, and comprehensive health benefits

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