Senior Scientist, In Vitro Biology Specialist

3 weeks ago

Vancouver, British Columbia, Canada Zymeworks Full time
Job Summary

We are seeking a highly skilled Associate Scientist, In Vitro Biology to join our team at Zymeworks. The successful candidate will be responsible for overseeing the design, coordination, and execution of in vitro pharmacology experiments for the screening and progression of novel technologies for ADCs.

Key Responsibilities
  • Design, coordinate, and execute in vitro pharmacology experiments for the screening and progression of novel technologies for ADCs.
  • Functionally characterize small molecules, antibodies, bioconjugates, or ADCs using various cell-based assays and techniques, including flow cytometry, high-throughput screening, live cell imaging, 3D tissue culture, and other methods as required.
  • Lead and execute novel assay development initiatives, designing and troubleshooting novel methods to profile the mechanism of action of ADCs across multiple payload classes.
  • Apply knowledge of cancer biology, medicinal chemistry, and other scientific methodologies in conducting technically advanced analyses and data interpretations.
  • Effectively collaborate with members outside of their immediate team to coordinate the execution of decision-making experiments for different projects and routinely share progress updates with the team.
  • Prepare and disseminate data presentations for group meetings, summarizing results and next steps, and act as area representative in specific projects.
  • Provide leadership, mentorship, and scientific/technical guidance to junior staff.
  • Support mammalian tissue culture activities within the group, working with the team to ensure cell lines are properly expanded, cryopreserved, and databases updated as required.
  • May co-author or author scientific papers, conference disclosures, patents, and/or regulatory documents, and may present at relevant scientific conferences on behalf of Zymeworks.
  • Adhere to Zymeworks' standard procedures for generating, documenting, and archiving data, maintaining an accurate, up-to-date electronic laboratory notebook.
  • Conduct all activities in accordance with scientific standards, OS&H regulations, and established Zymeworks' policies and practices, contributing to a safe and highly efficient laboratory environment.
  • Actively work to foster an environment of effective and collaborative working relationships amongst employees, management, and external partners.
Requirements
  • PhD in Molecular Biology, Immunology, Biochemistry, or equivalent combination of education and work experience.
  • Demonstrated experience with cell-based or biochemical assay development.
  • Demonstrated understanding of in vitro cancer models and therapeutic mechanisms of actions.
  • Experience with characterization and analysis of biotherapeutics (small molecules, antibodies, Fc-fusion proteins, ADCs, or other immunoconjugates) is an asset.
  • Experience with high-throughput screening assays and workflows is an asset.
Skills and Abilities
  • Ability to manage multiple projects, prioritize work, allocate resources, and deliver on deadlines.
  • Excellent analytical and problem-solving capabilities.
  • Adhere to the highest degree of professional standards and strict confidentiality on matters that require discretion.
  • Strong organizational and time management skills, working effectively in a fast-paced, fast-changing environment.
  • Excellent interpersonal skills, with the ability to work collaboratively as a member of a cross-functional team, and establish and maintain effective working relationships.
  • Excellent communication skills, including scientific/technical writing and oral skills, with the ability to present data effectively at large team meetings or interdepartmental meetings.
  • Demonstrated leadership and mentorship skills.
  • Results-oriented.
  • In-depth knowledge of antibody or antibody drug conjugate structure/function.
  • Knowledge of GraphPad and FlowJo software, or similar software, is considered an asset.
  • Advanced knowledge and proficiency in the following techniques: flow cytometry, high-content analysis or fluorescence imaging, mammalian tissue culture, immunological/co-culture assays, is considered an asset.
Total Rewards

We offer a comprehensive total rewards package, which includes competitive salaries, generous benefits, an outstanding work environment, and excellent opportunities for professional growth. We regularly benchmark our compensation against leading biotechnology companies in our geographies. The Canadian base salary range for this full-time position is $86,000 - $120,000, plus bonus, equity, and benefits. Our salary ranges are determined by role, level, and location. The range displayed on each job posting reflects the minimum and maximum target for new hire salaries for the position across all Canadian locations. Within the range, individual pay is determined by a variety of factors and the salary offered may vary depending on the successful candidate's location and qualifications.

Our team enjoys:

  • Industry-leading vacation and paid time off.
  • Excellent health and wellness benefits.
  • Zymelife health and wellness benefits.
  • Paid time off to volunteer in your community.
  • Matching RRSP/K program.
  • Employee Share Purchase Program.
  • Employee Equity Program.

All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin, or disability.

  • Senior Scientist, In Vitro Biology Expert

    1 month ago

    Vancouver, British Columbia, Canada Zymeworks Full time

    Job SummaryWe are seeking a highly skilled Associate Scientist to join our In Vitro Biology team at Zymeworks. As a key member of our team, you will be responsible for designing, coordinating, and executing in vitro pharmacology experiments to support the development of novel technologies for ADCs.Key ResponsibilitiesDevelop and implement novel assay...

  • Senior Scientist, In Vitro Biology Expert

    1 month ago

    Vancouver, British Columbia, Canada Zymeworks Full time

    Job SummaryWe are seeking a highly skilled Associate Scientist to join our In Vitro Biology team at Zymeworks. As a key member of our team, you will be responsible for designing, coordinating, and executing in vitro pharmacology experiments to support the development of novel technologies for ADCs.Key ResponsibilitiesDevelop and implement novel assay...

  • Senior In Vitro Biology Research Associate

    3 days ago

    Vancouver, British Columbia, Canada Zymeworks Full time

    Key ResponsibilitiesDesign, coordinate, execute, and analyze in vitro pharmacology experiments for novel technologies in ADCs, ensuring seamless screening and progression.Functionally characterize small molecules, antibodies, bioconjugates, or ADCs using cell-based assays and techniques like flow cytometry, high-throughput screening, live cell imaging, 3D...

  • Structural Biology Scientist

    1 week ago

    Vancouver, British Columbia, Canada AbCellera Full time

    Research Scientist - Computational Structural BiologyAbCellera is a leading biotech company that discovers and develops antibody-based medicines.As a Research Scientist in our Computational Structural Biology team, you will play a key role in designing, implementing, and evaluating in-silico protein engineering activities.Your primary responsibilities will...

  • Scientist in Cancer Biology

    1 month ago

    Vancouver, British Columbia, Canada PHSA Full time

    Job Title: Scientist in Cancer BiologyWe are seeking an exceptional Scientist in Cancer Biology to join our team at the British Columbia Cancer Research Institute (BCCRI). As a key member of our research team, you will contribute to the development of innovative cancer treatments and therapies.About the Role:The successful candidate will have a strong...

  • Scientist in Cancer Biology

    1 month ago

    Vancouver, British Columbia, Canada PHSA Full time

    Job Title: Scientist in Cancer BiologyWe are seeking an exceptional Scientist in Cancer Biology to join our team at the British Columbia Cancer Research Institute (BCCRI). As a key member of our research team, you will contribute to the development of innovative cancer treatments and therapies.About the Role:The successful candidate will have a strong...

  • Scientist in Cancer Biology

    4 weeks ago

    Vancouver, British Columbia, Canada PHSA Full time

    Job Title: Scientist in Cancer BiologyWe are seeking an exceptional Scientist in Cancer Biology to join our team at the British Columbia Cancer Research Institute (BCCRI). The successful candidate will have a proven track record of research excellence in cancer biology, with a focus on tumour development, cell plasticity, and metastasis.Key...

  • Scientist in Cancer Biology

    4 weeks ago

    Vancouver, British Columbia, Canada PHSA Full time

    Job Title: Scientist in Cancer BiologyWe are seeking an exceptional Scientist in Cancer Biology to join our team at the British Columbia Cancer Research Institute (BCCRI). The successful candidate will have a proven track record of research excellence in cancer biology, with a focus on tumour development, cell plasticity, and metastasis.Key...

  • Scientist in Cancer Biology

    4 weeks ago

    Vancouver, British Columbia, Canada PHSA Full time

    Job Title: Scientist in Cancer BiologyWe are seeking an exceptional Scientist in Cancer Biology to join our team at the British Columbia Cancer Research Institute (BCCRI). As a key member of our research team, you will contribute to the development of innovative cancer treatments and therapies.About the Role:The successful candidate will have a strong...

  • Scientist in Cancer Biology

    4 weeks ago

    Vancouver, British Columbia, Canada PHSA Full time

    Job Title: Scientist in Cancer BiologyWe are seeking an exceptional Scientist in Cancer Biology to join our team at the British Columbia Cancer Research Institute (BCCRI). As a key member of our research team, you will contribute to the development of innovative cancer treatments and therapies.About the Role:The successful candidate will have a strong...

  • Scientist, Cancer Biology Researcher

    2 weeks ago

    Vancouver, British Columbia, Canada PHSA Full time

    Research Scientist Opportunity in Cancer BiologyBC Cancer is seeking an exceptional Research Scientist to join our team in Cancer Biology. As a Research Scientist, you will be responsible for conducting cutting-edge research in cancer biology, with a focus on tumour development, cell plasticity, and metastasis.Key Responsibilities:Conduct research in cancer...

  • Senior Research Scientist

    3 weeks ago

    Vancouver, British Columbia, Canada Danaher Full time

    About the RoleWe are seeking a highly skilled and experienced Senior Research Scientist to lead our Nucleic Acid Therapeutics team. As a key member of our Biotechnology segment, you will be responsible for driving innovation and advancing future therapeutics from discovery to delivery.Key ResponsibilitiesPlan and execute projects for process and technology...

  • Senior Research Scientist

    1 month ago

    Vancouver, British Columbia, Canada AbCellera Full time

    About the RoleWe are seeking a highly motivated Senior Research Scientist with a strong background in oncology and immunology to join our team at AbCellera. As a key member of our research team, you will contribute to the assessment and development of antibody-based oncology drug candidates, driving our mission to bring innovative medicines to patients.Key...

  • Senior Research Scientist

    1 month ago

    Vancouver, British Columbia, Canada AbCellera Full time

    About the RoleWe are seeking a highly motivated Senior Research Scientist with a strong background in oncology and immunology to join our team at AbCellera. As a key member of our research team, you will contribute to the assessment and development of antibody-based oncology drug candidates, driving our mission to bring innovative medicines to patients.Key...

  • Research Scientist

    2 months ago

    Vancouver, British Columbia, Canada AbCellera Full time $75,200 - $94,000

    Research Scientist - Computational Structural BiologyAbCellera is a cutting-edge biotech company that discovers and develops antibody-based medicines. We are seeking a highly motivated Research Scientist to join our team and contribute to our innovative research in computational structural biology.Key Responsibilities:Design, implement, and evaluate...

  • Research Scientist

    2 months ago

    Vancouver, British Columbia, Canada AbCellera Full time $75,200 - $94,000

    Research Scientist - Computational Structural BiologyAbCellera is a cutting-edge biotech company that discovers and develops antibody-based medicines. We are seeking a highly motivated Research Scientist to join our team and contribute to our innovative research in computational structural biology.Key Responsibilities:Design, implement, and evaluate...

  • Scientist - Cancer Biology Specialist

    2 weeks ago

    Vancouver, British Columbia, Canada PHSA Full time

    Cancer Research Scientist PositionBC Cancer is seeking an outstanding candidate for a full-time position at the rank of Scientist at the British Columbia Cancer Research Institute (BCCRI). The BCCRI is a research institute of the University of British Columbia (UBC) and the Provincial Health Services Authority (PHSA).The successful candidate will be expected...

  • Cancer Biology Research Scientist

    9 hours ago

    Vancouver, British Columbia, Canada PHSA Full time

    Scientist Position in Cancer BiologyAt PHSA, we are seeking a highly skilled and dedicated Scientist to join our team in Cancer Biology. As a key member of our research team, you will be responsible for conducting innovative research in cancer biology, with a focus on tumour development, cell plasticity, and metastasis.Key Responsibilities:Design and conduct...

  • Senior Research Scientist

    1 month ago

    Vancouver, British Columbia, Canada AbCellera Full time

    About the RoleWe are seeking a highly motivated Senior Research Scientist to join our team at AbCellera. As a key member of our research team, you will contribute to the assessment and development of antibody-based oncology drug candidates, driving our mission to bring innovative medicines to patients.Key ResponsibilitiesLead internal preclinical in vivo...

  • Senior Research Scientist

    1 month ago

    Vancouver, British Columbia, Canada AbCellera Full time

    About the RoleWe are seeking a highly motivated Senior Research Scientist to join our team at AbCellera. As a key member of our research team, you will contribute to the assessment and development of antibody-based oncology drug candidates, driving our mission to bring innovative medicines to patients.Key ResponsibilitiesLead internal preclinical in vivo...