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Ottawa, Ontario, Canada Ottawa Hospital Research Institute Full timeAbout the Ottawa Hospital Research InstituteThe Ottawa Hospital Research Institute is a leading Canadian hospital-based research institute, affiliated with the University of Ottawa and supported by The Ottawa Hospital Foundation. With a strong focus on translating discoveries and knowledge into better health, our research spans over a hundred different...
Research Scientist
1 month ago
About the Ottawa Hospital Research Institute
The Ottawa Hospital Research Institute is a leading research arm of The Ottawa Hospital, one of Canada's largest learning and research hospitals. We are proudly affiliated with the University of Ottawa and supported by The Ottawa Hospital Foundation. Our research spans over a hundred different diseases, conditions, and specialties, with a focus on translating discoveries and knowledge into better health.
Job Description
We are seeking a highly motivated and knowledgeable Masters or PhD student in the Department of Cellular & Molecular Medicine to join our research team. Our research focuses on understanding the molecular and cellular mechanisms that regulate neural stem cell reprogramming and differentiation. We aim to define ways to recruit stem cells that are resident in the brain or derived from non-neuronal cells, with the goal of promoting neural repair. We are currently using stroke, Alzheimer's disease, and autism as brain disease models to explore underlying molecular mechanisms.
Key Responsibilities
- Conduct molecular, cellular, biochemical, and behavioral experiments using transgenic mouse models, in vivo neurodegenerative disease models, human iPSC-derived NPC cultures, and single-cell RNA-seq approaches.
- Develop and maintain laboratory techniques, including cloning, mutagenesis, PCR, cell line or primary cell culture, immunohistochemistry, and immunocytochemistry.
- Collaborate with the research team to design and implement experiments, analyze data, and interpret results.
- Communicate research findings through written reports and presentations.
Requirements
- Experience in molecular biology, cell biology, or in vivo animal model study.
- Excellent academic record and research experience.
- Strong written and oral communication skills.
Preferred Qualifications
- Laboratory experience in tissue culture and small animal experiments.
