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Vice President of Scientific Affairs
2 months ago
Remote Work Opportunity for Vice President of Scientific Affairs:
Apogee Pharmaceuticals, Inc. is a dynamic and innovative biotechnology firm located in Greater Vancouver, British Columbia, Canada.
The selected candidate will have the flexibility to work remotely from Canada or the United States, with a commitment to travel to Vancouver as needed.
Compensation Package:The successful candidate will be offered a competitive compensation package that includes both salary and an attractive incentive program based on achievable goals, such as securing funding and establishing drug licensing agreements with major pharmaceutical companies.
This structure allows for immediate financial benefits, unlike traditional stock options that may take time to realize.
Company Overview:
Apogee is a well-capitalized, science-oriented biotechnology company focused on the discovery and development of groundbreaking small molecule therapies aimed at treating neurological, inflammatory, and metabolic disorders.
Currently, Apogee's projects are in the early stages of development, primarily targeting the endocannabinoid system, with plans to broaden its research scope in the future.
Position Overview:
We are seeking a highly qualified scientist to fill the role of Vice President of Scientific Affairs, responsible for steering our early-stage drug discovery initiatives.
This pivotal leadership position will oversee all scientific endeavors and contribute to shaping the strategic direction of Apogee.
The Vice President will lead research teams to achieve discovery, preclinical, and early clinical objectives.This role emphasizes scientific contributions over managerial duties, allowing the Vice President to focus primarily on scientific advancements in the immediate term.
This unique position offers the chance to make significant contributions in a vibrant scientific setting, collaborating closely with a talented scientific team and supportive executive management.
Apogee fosters a fast-paced and agile environment that prioritizes scientific problem-solving with minimal bureaucracy while ensuring sound decision-making.
The well-being and success of our scientific team are paramount to our leadership and stakeholders.Key Responsibilities:
From the outset, demonstrate a comprehensive understanding of the pharmacology of the endocannabinoid system (eCB) and a solid grasp of small-molecule inhibitors targeting eCB enzymes.
Conduct comparative analyses of Apogee's initiatives against industry competition and relevant scientific literature (SWOT analysis), focusing on clinical successes and setbacks.
Develop and execute Research Operating Plans for each project.Identify necessary in-house assay capabilities and determine tasks suitable for outsourcing. Collaborate with experts in DMPK, biology, pharmacology, toxicology, and other scientific disciplines to advance lead compounds.
Explore the expansion of clinical indications for existing programs and consider additional projects; evaluate potential in-licensing opportunities.
Lead a team of exceptional scientists across chemistry, biology, and analytical fields, providing scientific direction, technical oversight, mentorship, and career development.
Engage with scientists at collaborating contract research organizations (CROs) to enhance project outcomes.
Establish and nurture relationships with external partners, including CROs and academic institutions.
Generate novel intellectual property (IP), contribute to patent applications, and maintain a working knowledge of patent prosecution.
Stay informed about the latest trends and advancements in drug discovery and therapeutic areas critical to the company.
Attend relevant industry conferences and technical symposiums as necessary.Present findings and updates to executive leadership, investors, and other stakeholders.
Future responsibilities may include engaging with external investors, advisory boards, regulatory agencies, and pharmaceutical partners as appropriate.
Qualifications:
PhD in organic chemistry, medicinal chemistry, pharmacology, biology, or a related discipline, with over 15 years of progressive experience in the biotechnology or pharmaceutical sector; a proven track record as a 'drug hunter'.
pharmacology, chemistry, drug metabolism pharmacokinetics (DMPK), in vivo efficacy, safety & toxicology, and intellectual property (IP).
Exceptional problem-solving, critical thinking, and decision-making abilities, with a talent for managing multiple complex projects simultaneously.Strong leadership capabilities, including the ability to motivate, develop, and inspire a team of skilled scientists in chemistry and biology.
Excellent communication and presentation skills, with the capacity to convey complex scientific concepts to both technical and non-technical audiences.
An entrepreneurial mindset and a dedication to the advancement of innovative therapeutics.