Research Associate, Protein Biochemistry

2 weeks ago

Vancouver, Canada Gandeeva Therapeutics Inc. Full time

Gandeeva Therapeutics is a rapidly growing precision biotechnology company located in Greater Vancouver, BC, Canada harnessing the power of cryo-EM technology and machine learning to advance drug discovery and development at scale. Gandeeva seeks to achieve transformative societal impact on public health by revolutionizing drug discovery and by lowering the risk of late-stage clinical failures. Our unique and world-leading AI-enabled cryo-EM drug discovery platform combines deep biochemical and structural knowledge to target the most important protein sites and translates this knowledge into superior precision medicines for patients.

We are expanding our interdisciplinary and innovative team of biologists, chemists, microscopists, engineers, software developers and business professionals who work closely together in a state-of-the-art facility that provides a stimulating environment and reflects our inclusive and welcoming culture. Join us on our mission to bring new treatment options to patients by revolutionizing drug discovery

We are seeking a** **highly motivated **Research Associate **as part of a team working in a world class state-of-the art laboratory who will be involved protein expression, purification, and analysis to support Gandeeva's drug discovery efforts.

**Responsibilities**:

- Establish and implement gene-to-protein workflows to reliably express target proteins for structural biology and for use in drug discovery processes.
- Analyze purified proteins using biophysical and biochemical techniques.
- Participate in structure determination and interpretation using cryo-EM, X-ray crystallography and NMR approaches.
- Perform other related duties as required and as assigned.

**Qualifications and Experience**:

- MSc in a relevant discipline with several years of related industry experience in the life sciences or biotechnology sector or an equivalent combination of training and experience.
- Expertise in recombinant protein expression in mammalian, insect, and/or microbial cell lines.
- Expertise in purifying a range of different protein types using multiple chromatographic methods.
- Familiarity in recombinant DNA techniques.
- Familiarity with biophysical methods for protein interaction or binding.
- Familiarity with protein enzymatic activity or function where appropriate.
- Demonstrated ability to work to a high level of personal and professional integrity and ethics.
- Excellent written and verbal communication skills, including the ability to communicate with scientific and non-scientific personnel.
- Strong quantitative and analytical skills.
- Excellent attention to detail with strong critical thinking and decision-making abilities.
- Excellent time management skills with the ability to prioritize and meet deadlines.
- Ability to multitask and thrive in a fast-paced environment with changing priorities.
- Must be an independent self starter who is also an excellent team player with strong interpersonal skills.
- Must be adaptable and flexible to work collaboratively and effectively in a multi-disciplinary environment.

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