Scientist, Analytical Development

6 months ago

Vancouver, Canada Genevant Sciences Full time

**Company Profile**
Genevant is a technology-focused nucleic acid delivery company with world class platforms, the industry’s most robust and expansive lipid nanoparticle (LNP) patent portfolio, and decades of experience and expertise in nucleic acid drug delivery and development. We have laboratories and a key office based in beautiful Vancouver, British Columbia.

We leverage our innovative delivery systems and related technologies to help bring new medicines to patients who need them. We do this by selectively collaborating with leading pharma and biotech companies and fostering a culture of innovation that allows us to maintain our leadership position in the space. If you find that inspiring, we want to work with you

**Position Summary - Scientist**

**Responsibilities**:

- Develop robust and scientifically sound analytical methods for release and stability testing of lipid excipients, nucleic acid drug substances and LNP drug products.
- Investigate novel methods for characterization of LNP.
- Assess the performance of new analytical methods to ensure suitability for their intended purpose. Prepare analytical test method documents and analytical development reports summarizing development history and method performance.
- Assist in the identification and management of external collaborating parties and/or contract research laboratories.
- Conduct detailed data analyses and generate comprehensive written reports of studies.
- Present scientific results in a variety of settings, both formal and informal, and both within and outside of Genevant.
- Write and generate study reports, presentations, and publications.
- Independently stay aware of the current literature in the field
- Summarize findings in written reports and present results at internal meetings.
- Perform other activities related to the function as assigned by manager.***

**Requirements, **Knowledge, skills, and abilities**:

- Ph.D (or MSc. with 3+ years’ experience) in Analytical Chemistry, Chemistry, Pharmaceutical Science or a related discipline.
- Knowledge of analytical methods used to characterize lipids, mRNA and/or oligonucleotides (e.g. Lipid HPLC analysis, Oligonucleotide IP-RP LC analysis, Ribogreen assay, particle size determination).
- Experience with lipid nanoparticle characterization and HPLC and mass spectrometry (LC-MS, GC-MS) analysis is preferred.
- Knowledge of statistical analysis, including data trending.
- Knowledge of ICH Guidelines and related regulatory guidances, and cGMP, is an asset.
- Excellent verbal and written communication skills; experience with development report generation and authoring of regulatory submissions.
- Excellent interpersonal skills; mature with a proven ability to work well with others throughout a diverse organization.
- Ability to manage deadlines and prioritize effectively, while maintaining flexibility.
- Ability to work independently with mínimal supervision, take initiative and take on responsibility for projects.

**Benefits & Compensation**
We’ve worked to create an environment at Genevant that makes our people feel empowered, supported and appreciated so they can focus on doing incredible work that can change the future. To that end, we offer competitive salaries, performance bonus opportunity, as well as a generous benefits package including health, dental, vision, wellness, short
- & long-term disability, accident death & dismemberment, and life insurance programs; company match towards retirement savings, equity participation, and ample time off through our flexible PTO and annual company shutdown

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