Associate Scientist, Analytical Development

3 months ago


Vancouver, Canada AbCellera Full time

AbCellera is breaking the barriers of conventional drug development to propel antibody-based medicines from target to clinic. We are a team of scientists, engineers, creatives, and business professionals who believe that advancing science enhances lives. We have developed technologies to unlock high-value drug targets, including antibody-drug conjugates and T-cell engagers for cancer, and complex transmembrane proteins for indications such as metabolic and endocrine conditions, pain, and autoimmunity.

We are seeking a highly motivated Associate Scientist to join Analytical Development within the Process Analytics team at AbCellera. In this role, you will be responsible for assisting in establishing and running platform high throughput analytical methods in support of Process Development. This will include execution of methods such as size variant analysis, glycan analysis, charge heterogeneity, size variant analysis by R/NR-CE-SDS, HCP, HC DNA, and Residual Protein A quantitation.

**How you might spend your days**:

- Performing routine analyses of samples in support of Process Development through fulfillment of requests delivered through our ELN
- Running a variety of analytical techniques including LC, CE, iCIEF, UV-Vis, ELISA, and qPCR
- Identifying and implementing opportunities for lab efficiencies (Ex. automated documentation, data analysis, data reporting, etc)
- Aggregating and presenting analytical data to stakeholders across CMC teams and within Analytical Operations
- Researching and evaluating technological advances in the field of high throughput analytical techniques
- Managing an analytical request schedule; designing experimental plans that aggregate multiple requests to better deliver results in a timely manner
- Working with AbCellerties across Analytical Development to develop new methods with higher throughput and accuracy; performing method qualifications where and when appropriate
- Updating, innovating, and implementing new experimental protocols as necessary to improve productivity in Process Analytics

**We'd love to hear from you if**:

- You have a B.S. in Analytical Chemistry, Biochemistry or related discipline with 2+ years experience or a master's with 0-2 years of experience
- You have experience working in areas of therapeutic protein analysis in either academia or industry
- You have a proven problem-solver and team player with strong written and verbal communication skills
- You have strong data and time organization/management skills, with attention to details
- You have technical proficiency in separation based analytical method development and qualification including SEC, IEX, RP, HILIC, CE-SDS, and icIEF methods
- You have familiarity with electronic lab notebooks, experimental data capture, electronic signatures
- You have demonstrated the ability to learn, understand and master new experimental techniques
- You have familiarity with CMC analytical development of monoclonal antibodies or related biotherapeutic proteins (beneficial)
- You have knowledge of regulatory filings such as INDs, BLAs, IMPDs, etc (beneficial)

**What we offer**

AbCellera's hiring range for this role is CAD $60,500 - $75,600 annually, commensurate with your education and job-related knowledge, skills, and experience. In addition to base salary, we offer equity, annual bonus dependent on team and company performance, and a 6% (non-match) RRSP contribution.

You will have a CAD $1,500 annual Active Lifestyle Allowance, annual vacation, professional development opportunities, and comprehensive health benefits. Scientific and technical mentorship is a priority. And you'll find we prioritize teams and social groups to build community and connections across AbCellera.

**About AbCellera**

AbCellera is a global company that discovers and develops antibody-based medicines that help people live longer, happier, and more productive lives. We are focused on bringing innovative medicines to patients, both by advancing our internal pipeline of programs and partnering with companies that have novel science or innovative technology.

And it all starts with our team. We've built a place where people feel they are part of something bigger than themselves. A place that exists to push the limits of science and technology, and aims to bring better therapies to patients.

We look for people with drive and energy. Idealists. People we love and people we trust. This may be unconventional, but it is the key to our success.

**To apply



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