Corporate Data Management Director

1 month ago


Mississauga, Canada AstraZeneca GmbH Full time
p>Job Title: Director, Epidemiology - Hematology and Nephrology

Location: Mississauga, ON

Alexion Canada

Since beginning our operations in Canada in 2009, Alexion has been working tirelessly to bring innovative medicines to the millions of Canadians living with rare diseases. Our pioneering 30-year legacy, our scientific expertise and our commitment to patient-centric decision-making are the foundations of what we are today – a company with a mission to transform lives.

Our Canadian team

We know that people living with a rare disease and their families deserve our unwavering commitment and investment into finding and accessing therapies that help them live longer, fuller lives. Our presence in Canada has grown to over 200 employees and includes a global research and development hub, made up of highly skilled professionals responsible for conducting our clinical trials in Canada and around the world, as well as our dedicated and passionate local teams that ensure our treatments reach those who need them. p>

How we work
When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. That’s why we work, on average, a minimum of three days per week from the office. But that doesn’t mean we’re not flexible. We balance the expectation of being in the office while respecting individual flexibility. p>

This is what you will do:

The Director, Epidemiology is a senior strategic and scientific leadership role that provides global direction and expertise for epidemiology support for programs within the therapeutic areas of Hematology and Nephrology. This role partners with cross-functional stakeholders to ensure appropriate epidemiological perspectives are provided in support of strategic needs and integrated into corporate plans. They are accountable for developing and implementing innovative, effective and impactful epidemiology deliverables, ensuring all deliverables are performed efficiently, commensurate with budget, quality, accuracy, timeliness, and in accordance with current advancements in epidemiology / pharmacoepidemiology methodology.

The role requires key interactions with senior leadership, routinely collaborating with leaders within Clinical Development, Patient Safety, Regulatory Affairs, Commercial / Marketing, Health Economics and Outcomes Research, Medical Affairs, Project Management, along with Global Program Team Leaders.

Therefore, demonstrated experience in collaborating across functions in order to meet project objectives is key, along with the ability to assess and address team member needs through the use of skills such as influence, conflict resolution and negotiation. They may also be called upon to represent the Epidemiology and Real World Science department in interactions with external stakeholders, such as Scientific Advisory Boards or regulatory authorities.

You will be responsible for:

  • Accountable for developing plan for Epidemiology deliverables (e.g. systematic literature reviews, database studies, analysis within primary observational studies/disease registries, PASS/PMCs, REMS/RMPs) for assigned indications within the therapeutic areas to support company objectives.
  • Accountable for executing deliverables in accordance with the plan, either personally or through oversight of other Epidemiologists/vendors/contractors.
  • Accountable for providing epidemiology support to Clinical Development, Patient Safety, Regulatory Affairs, Medical Affairs, and Commercial activities across the product life cycle. li>
  • Accountable for ensuring epidemiology perspective into company materials e.g. study protocols, case report forms (CRFs), and regulatory documents within assigned indications within the therapeutic areas.
  • Interact with authors and in-house reviewers on scientific manuscripts, clinical conference abstracts, presentations, and posters based on observational study data.
  • Represent Epidemiology and Real World Science department during interactions with key external stakeholders including Scientific Advisory Boards and regulatory authorities.
  • Maintain awareness of epidemiology with respect to regulatory requirements, payer trends, and advancement of pharmacoepidemiology methods.
  • Represent Epidemiology and Real World Science department and participate in corporate cross-functional business / process improvement initiatives.
  • Actively participates in development and maintenance of Epidemiology and Real World Science department Standard Operating Procedures / Process Guides.

You will need to have:

  • PhD / DSc / DrPH in Epidemiology with at least 6 years proven experience in the pharmaceutical industry, biotechnology, or consulting environment, or MPH/MSc in Epidemiology with at least 10 years proven experience in the pharmaceutical industry, biotechnology, or consulting environment.
  • The duties of this role are generally conducted in an office environment. As is typical of an office-based role, employees must be able, with or without an accommodation to: use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving and non-linear thought, analysis, and dialogue; li>

We would prefer for you to have:

  • Excellent oral and written communication skills
  • Knowledge of drug and clinical development process for genomic medicines
  • Excellent attention to detail and quality, and scientific rigor
  • Strong communication skills and ability to work effectively in multidisciplinary teams
  • High degrees of self-motivation and organization
  • Comfort in a fast paced environment with frequent changes in scope or direction of projects
  • Thorough and up-to-date technical knowledge of epidemiology and relevant biostatistics methods
  • Experience and familiarity using SAS or other statistical software packages
  • Evidence of productivity in epidemiological research as demonstrated by successful design, execution, and publication of epidemiological research, including through extensive collaboration with external investigators
  • 2 years of line management or supervisory experience or equivalent
  • Record of high-quality publications in peer-reviewed journals

Alexion embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. Alexion is committed to accommodating persons with disabilities. Such accommodation is available on request in respect of all aspects of the recruitment, assessment and selection process and may be requested by emailing AZCHumanResources@astrazeneca.



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