Postdoctoral Research

19 hours ago


Calgary, Canada University of Calgary - Calgary Prion Research Unit Full time
p>The University of Calgary’s Calgary Prion Research Unit, Dr. Sabine Gilch lab, is seeking to recruit two postdoctoral researchers to carry out exciting projects related to cell biology of prion infection and molecular mechanisms and pathogenesis of chronic wasting disease (CWD), a prion disease of cervids.The goals of our research are to understand the impact prion conversion and accumulation affects neuronal metabolism, which host factors determine the evolution of prion strains in CWD, and how we can use this knowledge to develop tools to treat prion diseases in humans and mitigate the spread of CWD.Postdoctoral fellow 1 will use a range of cell and ex vivo models of prion infection, including primary neurons and organotypic slice cultures, to determine the impact of prion infection on endocytic pathways, membrane properties, and stress responses in prion infection, depending on cell type and prion strain.Postdoctoral fellow 2 will use gene-targeted mouse models of CWD established by our lab, conventional transgenic mice and cell culture models as well as in vitro prion amplification methods (RT-QuIC and PMCA) to study mechanisms underlying strain evolution in different transmission routes, prion protein polymorphisms and tissue environment.Projects are funded by the Canadian Institutes of Health Research (CIHR) and the Natural Sciences and Engineering Research Council (NSERC) of Canada for > 2 years. Postdoctoral fellows in the Gilch lab are part of our faculty's vibrant postdoctoral community which offers a variety of career development events and regular networking meetings.PhD in biochemistry, neuroscience, infectious diseases or related fields obtained within the last 2 years Strong interest in prions and neurodegenerative diseases, previous experience with prions, prion-like diseases and methods such as BioID are considered an asset

The Gilch lab values an inclusive, friendly, respectful and non-discriminatory working environment, and candidates are expected to adhere to these principles.



  • Calgary, Alberta, Canada University of Calgary - Calgary Prion Research Unit Full time

    Job Title: Postdoctoral Fellow in Prion ResearchThe University of Calgary's Calgary Prion Research Unit, Dr. Sabine Gilch lab, is seeking to recruit two postdoctoral researchers to carry out exciting projects related to cell biology of prion infection and molecular mechanisms and pathogenesis of chronic wasting disease (CWD), a prion disease of...


  • Calgary, Alberta, Canada University of Calgary - Calgary Prion Research Unit Full time

    Job Title: Postdoctoral Fellow in Prion ResearchThe University of Calgary's Calgary Prion Research Unit, Dr. Sabine Gilch lab, is seeking to recruit two postdoctoral researchers to carry out exciting projects related to cell biology of prion infection and molecular mechanisms and pathogenesis of chronic wasting disease (CWD), a prion disease of...


  • Calgary, Alberta, Canada University of Calgary - Calgary Prion Research Unit Full time

    Job Title: Postdoctoral Fellow in Prion ResearchThe University of Calgary's Calgary Prion Research Unit, Dr. Sabine Gilch lab, is seeking to recruit two postdoctoral researchers to carry out exciting projects related to cell biology of prion infection and molecular mechanisms and pathogenesis of chronic wasting disease (CWD), a prion disease of...


  • Calgary, Alberta, Canada University of Calgary - Calgary Prion Research Unit Full time

    Postdoctoral Researchers Needed for Prion Disease Research We are seeking two highly motivated postdoctoral researchers to join our team at the University of Calgary's Calgary Prion Research Unit, Dr. Sabine Gilch lab. Our research focuses on understanding the cell biology of prion infection and the molecular mechanisms underlying chronic wasting disease...


  • Calgary, Alberta, Canada University of Calgary - Calgary Prion Research Unit Full time

    Job OpportunityThe University of Calgary's Calgary Prion Research Unit, Dr. Sabine Gilch lab, is seeking to recruit two postdoctoral researchers to carry out exciting projects related to cell biology of prion infection and molecular mechanisms and pathogenesis of chronic wasting disease (CWD), a prion disease of cervids.Research FocusPrions are protein-only...


  • Calgary, Alberta, Canada University of Calgary - Calgary Prion Research Unit Full time

    Job OpportunityThe University of Calgary's Calgary Prion Research Unit, Dr. Sabine Gilch lab, is seeking to recruit two postdoctoral researchers to carry out exciting projects related to cell biology of prion infection and molecular mechanisms and pathogenesis of chronic wasting disease (CWD), a prion disease of cervids.Research FocusPrions are protein-only...

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