Research Assistant/technician 4

5 days ago

Vancouver, British Columbia, Canada UBC Full time
Research Assistant/Technician 4 Job Title: Research Assistant/Technician 4 Department: Strynadka Laboratory | Department of Biochemistry and Molecular Biology | Faculty of Medicine Job Summary:

This position is required to support day-to-day macromolecular sample preparation for structural biology as well as infrastructure operation and eventual user training in the High Resolution Macromolecular EM Facility at UBC. The successful candidate will assist with operation of a variety of instrumentation required for sample production and high-resolution single-particle electron microscopy sample preparation.

Key Responsibilities:
  • Undertake standard molecular biology and protein overexpression, purification procedures to create high-yield, high-purity proteins for structural biology applications.
  • Oversee, operate, maintain, and train users on a 120 keV Talos TEM instrument in both room temperature and cryo modes.
  • Responsible for handling and clipping cryoEM grids in preparation for imaging, as well as handling of cryoEM grids for transfer to multi-sample autoloader capsules.
  • Oversee, maintain, and train users on a VitroBot and other vitrification equipment.
  • Work with lab members and users to troubleshoot problems and answer queries.
  • Oversee and perform logistical tasks, including organizational tasks, equipment maintenance and oversight, user session scheduling, placing orders, handling liquid nitrogen, and tracking usage.
  • Assist with lab and facility communication, including website population and design and creation or update of standardized operational procedure documentation.
Requirements:
  • Completion of a university degree in a relevant discipline or technical program and a minimum four years of related experience or an equivalent combination of education and experience.
  • Willingness to respect diverse perspectives, including perspectives in conflict with one's own.
  • Demonstrates a commitment to enhancing one's own awareness, knowledge, and skills related to equity, diversity, and inclusion.
Preferred Qualifications:
  • Undergraduate degree in a relevant discipline, or graduation from a technical college or institute is required.
  • A MSc in a relevant discipline is preferred.
  • Prior expertise of sample preparation for structural biology, including membrane proteins, is preferred, as is knowledge of the general work flow of single-particle cryoEM.
About UBC:

At UBC, we believe that attracting and sustaining a diverse workforce is key to the successful pursuit of excellence in research, innovation, and learning for all faculty, staff, and students. Our commitment to employment equity helps achieve inclusion and fairness, brings rich diversity to UBC as a workplace, and creates the necessary conditions for a rewarding career.

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