Highly Motivated Protein Mass Spectrometry Researcher
6 days ago
At AbCellera, we're pushing the boundaries of conventional drug development to bring life-changing antibody-based medicines from target to clinic.
We're a team of driven scientists, engineers, creatives, and business professionals who believe that advancing science enhances lives. With cutting-edge technologies, we unlock high-value drug targets, including antibody-drug conjugates and T-cell engagers for cancer, and complex transmembrane proteins for indications such as metabolic and endocrine conditions, pain, and autoimmunity.
We're seeking a highly motivated scientist with hands-on laboratory experience in characterizing antibodies and/or other therapeutic proteins using mass spectrometry and other analytical techniques. As a member of our multidisciplinary team, you'll thrive in a fast-paced work environment with multiple competing priorities, and drive scientific innovation to support the discovery of novel monoclonal antibodies for therapeutic use.
Your Key Responsibilities:
- Design, plan, and execute experiments independently or collaboratively with teammates
- Perform mass spectrometry analysis of antibodies and other therapeutic proteins, including intact mass, peptide mapping, glycan profile, and post-translational modification
- Conduct detailed protein structural interrogation, including sequence confirmation, variant identification, disulfide mapping, and chemical modifications
- Develop and perform analytical assays for protein characterization, including UPLC, light scattering, CE-SDS, and cIEF
- Train and mentor team members, solve complex problems, and communicate project updates and deliverables
- Develop and implement standard operating procedures, organize project timelines, and collaborate with partners
We're Looking for Someone Who:
- Has demonstrated expertise in protein mass spectrometry analysis, including intact mass and peptide mapping assays for identifying post-translational modifications on antibodies
- Possesses a PhD in Biochemistry, Structural Biology, or related field, or MSc with 5+ years in an academic or industry wet lab environment with emphasis on mass spectrometry
- Thinks critically, is curious, and wants to explore new technologies and automation to improve the antibody characterization workflow and process
- Has hands-on experience with sample preparation for mass spectrometry analysis and demonstrated experience in protein characterization using analytical chromatography, light scattering, thermal denaturation, or other analytical techniques
What We Offer:
Our hiring range for this role is CAD $75,200 - $94,000 annually, commensurate with your education and job-related knowledge, skills, and experience. In addition to base salary, we offer equity, annual bonus dependent on team and company performance, and a 6% RRSP contribution. You'll also receive a CAD $1,500 annual Active Lifestyle Allowance, annual vacation, professional development opportunities, comprehensive health benefits, and scientific and technical mentorship.
About AbCellera:
We're a global biotech company focused on bringing innovative medicines to patients by advancing our internal pipeline of programs and partnering with companies that have novel science or innovative technology. Our team prioritizes community, connections, and scientific innovation, and we're committed to making a meaningful impact on people's lives.
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Vancouver, British Columbia, Canada AbCellera Full timeAt AbCellera, we are pushing the boundaries of conventional drug development to accelerate the discovery of antibody-based medicines. Our team of scientists, engineers, and innovators is dedicated to advancing science and technology to improve human lives. We are seeking a highly motivated Research Scientist to join our multidisciplinary team and contribute...
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Vancouver, British Columbia, Canada AbCellera Full timeAt AbCellera, we're breaking the barriers of conventional drug development to propel antibody-based medicines from target to clinic.We're a team of scientists, engineers, creatives, and business professionals who believe that advancing science enhances lives. Our innovative technologies unlock high-value drug targets, including antibody-drug conjugates and...
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