Bioinformatics Research Associate I

**Position: Bioinformatics Research Associate I**
**Location: MaRS Centre, Toronto**
**Department: Computational Biology (Pai Lab)**
**Reports To: Dr. Shraddha Pai, Principal Investigator I**
**Salary: Commensurate with level of experience**

**Hours: 35 hours/week**
**Job Type: On-site**
**Status: Full-time, Temporary (2-year contract)**

The Ontario Institute for Cancer Research (OICR) is seeking an experienced professional to fill the key role of Bioinformatics Research Associate I within the **Computational Biology** Program.

This position is temporary, full-time for two-years with the possibility of conversion to a permanent position.

The Pai Lab uses cutting-edge computational and experimental genomic techniques to advance precision medicine in cancer. Our goal is to use genomics to match patients with the best treatment options, and to find novel molecular targets for precise therapy. We discover biomarkers by integrating clinical and multi-‘omic data from normal tissues and tumours, with prior knowledge of pathways, gene regulation, disease association, and druggability. We use established software workflows and develop novel algorithms for functional inference, and specialize in systems biology and network-based approaches. Our collaborations are interdisciplinary and include genome scientists, computational biologists, clinicians, and experts in drug discovery, and we are part of the world-class precision genomics community at OICR.

Fully vaccinated is defined as having received all of the required doses of a Health Canada approved vaccine and having received the final dose at least 14 days before your employment start date.

To learn more about working at OICR, visit our **career page**.

**The responsibilities include**:

- Develop and oversee high-throughput NGS pipelines for genomic assays such as WGBS, EM-seq, RNAseq, WGS, scRNA-seq, scATAC-seq, scMultiome-seq
- Analyze sequencing data from established pipelines
- Develop new computational methods to visualize, integrate, and interpret multi-omics data
- Help manage lab servers and computational infrastructure
- Document and present results in written or oral reports to lab members
- Contribute to the codebase, development, and support of open-source software packages
- Help onboard new lab members for computational and genomic analysis

**Qualifications**:

- Completion of a Master’s degree in computer science, bioinformatics, data science, engineering, or similar quantitative field, or equivalent education or work experience
- Experience in programming, including in data visualization, data table manipulation, and statistics, using a language for data analytics (e.g., R, Matlab, python).
- Experience with Unix/Linux
- Demonstrated exposure to genomics data analysis
- Excellent written and verbal communication skills
- Ability to thrive in a collaborative, team-based environment

OICR is a collaborative, not-for-profit research institute accelerating the development of new cancer research discoveries for patients around the world while maximizing the economic benefit of this research for the people of Ontario. We are dedicated professionals who bring expertise to each of our roles. We are looking for individuals who share our values of excellence, innovation, collaboration, impact, responsibility and community.

Launched in December 2005, OICR is an independent institute funded by the Government of Ontario through the Ministry of Colleges and Universities.


**CLOSING DATE: Until Filled**
- The Ontario Institute for Cancer Research thanks all applicants. However, only those under consideration will be contacted._

Note to applicants: In your resume, please provide a link to your programming portfolio (Github page or similar).