Bioinformatics Analyst

4 days ago

Toronto, Canada Public Health Ontario Full time

**JR100633**

**Union**: AMAPCEO

To provide technical and computational support for research and clinical operations with a focus on software development and management, quality control, analysis, transformation, visualization, and presentation of data. Support tasks and methods may eventually transition into standardized workflows.

**Key Responsibilities**:

- Provides support to researchers and clinicians in several bioinformatics domains such as sequencing (WGS/exome sequencing, RNA-seq, ChIP-seq and other OMICS technologies), genome assembly, annotation, variant analysis, comparative and population genomics, functional genomics, metagenomics, phylogenomics and in implementation of analyses into reproducible workflows.
- Provides support in public health data management in creating and maintaining databases, data warehouses and data marts.
- Provides support simultaneously to different projects and meeting deadlines, frequently in collaboration with other cores and research groups.
- Assist in maintaining tools and scientific libraries on Unix-based servers and develop analysis pipelines in Galaxy and/or in other workflow management systems.
- Provides support to users on a daily basis, assembling training materials (e.g. writing of wiki-based documentation/how-to) and organizing tutorials.
- Performs other related duties as assigned.

**Knowledge and Skills**:

- Expertise in conducting data analysis in the Next Generation Sequencing (NGS) data including data quality assessment, genome re-alignment, assembly and annotation, variation identification and characterisation, metagenomics, phylogenomics and comparative genomics.
- Highly skilled in scripting (Shell, Perl and Python), object-oriented programming (Java, C++ and Ruby), database administration (MySQL and PostgreSQL) and database development.
- Experience working in High Performance Computing clusters and cloud infrastructures.
- Knowledge in Big-Data platforms including NoSQL databases, Hadoop and associated technologies. Knowledge of Laboratory Information Systems and integrating those in support of bioinformatics clinical frameworks.

**Education and Experience**:

- Undergraduate degree in bioinformatics and/or computer science from an accredited university with 2-3 years of experience OR equivalent related education and experience. Graduate degree and experience with R programming language considered an asset.
- Specialized training in genomics, molecular biology and/or microbiology and knowledge of statistics, epidemiology, and public health.

**Attributes and Competencies**:

- Written communications skills to write technical reports, contribute towards scientific manuscripts and to create and maintain standard operating procedures,
- Oral communications skills to work with team colleagues in response to requests and directions in the analysis of data.
- Oral communication and interpersonal skills maintain linkages with external laboratories to facilitate collaboration.
- Provides bioinformatics services and support to research and clinical staff as directed by the manager.
- Maintains a highly responsive approach to meeting urgent requests for data analysis.
- Works proactively and cooperatively with internal stakeholders, understanding their needs and addressing challenges.

**Job Types**: Full-time, Permanent

Work Location: Hybrid remote in Toronto, ON

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