Research Scientist

3 weeks ago

Ottawa, Ontario, Canada Ottawa Hospital Research Institute Full time

About Us

The Ottawa Hospital Research Institute is a leading Canadian hospital-based research institute, affiliated with the University of Ottawa and supported by The Ottawa Hospital Foundation. Our research spans over a hundred different diseases, conditions, and specialties, with a focus on translating discoveries and knowledge into better health.

Job Description

We are seeking a highly motivated and enthusiastic Masters or PhD student in the Department of Cellular & Molecular Medicine to join our research team. Our research focuses on understanding the molecular and cellular mechanisms that regulate neural stem cell reprogramming and differentiation, with the goal of defining ways to recruit stem cells and promote neural repair. We are currently using stroke, Alzheimer's disease, and autism as brain disease models to explore underlying molecular mechanisms.

Key Responsibilities

  • Conduct molecular, cellular, biochemical, and behavioral experiments using transgenic mouse models, in vivo neurodegenerative disease models, human iPSC-derived NPC cultures, and single-cell RNA-seq approaches.
  • Develop and maintain laboratory techniques, including cloning, mutagenesis, PCR, cell line or primary cell culture, immunohistochemistry, and immunocytochemistry.
  • Collaborate with our research team to design and implement experiments, analyze data, and interpret results.
  • Present research findings in a clear and concise manner, both in writing and orally.

Requirements

  • Experience in molecular biology, cell biology, or in vivo animal model study.
  • Excellent academic record and research experience.
  • Excellent written and oral communication skills.

Preferred Qualifications

  • Laboratory experience in tissue culture and small animal experiments.

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