Research Scientist — Biophysical Characterization and Developability Expert

1 month ago


Vancouver, British Columbia, Canada AbCellera Full time
About the Role

We are seeking an experienced Research Scientist to join our team at AbCellera, a global leader in antibody-based medicines. As a key member of our team, you will play a critical role in advancing our pipeline of innovative therapies.

Key Responsibilities
  • Conduct in-depth characterization of antibodies, multispecifics, and antibody-drug conjugates using advanced analytical and biophysical techniques.
  • Assess the developability properties of lead molecules, including formulation, stability, and colloidal stability.
  • Analyze and interpret complex data sets to nominate lead candidate molecules for clinical development.
  • Provide scientific leadership and mentorship to junior scientists within our dynamic team.
  • Develop and implement new workflows for analytical and biophysical screening of antibody properties.
Requirements
  • PhD in Biophysics, Biochemistry, or Structural Biology, or a MSc degree plus 5+ years of relevant experience.
  • Hands-on experience with analytical SEC, HIC, IEX, light scattering, CE-SDS, cIEF, DSF, DSC, mass spectrometry, or related techniques.
  • Experience applying analytical techniques to assess protein sample quality and developability of biotherapeutics.
  • Strong understanding of protein sequence and structure, as well as common modifications and physical and chemical stability risks.
  • Excellent communication and interpersonal skills, with the ability to work collaboratively as a member of a cross-functional team.
What We Offer

AbCellera offers a competitive salary range of CAD $75,200 - $94,000 annually, commensurate with your education and job-related knowledge, skills, and experience. In addition to base salary, we offer equity, annual bonus dependent on team and company performance, and a 6% (non-match) RRSP contribution. You will also have access to a CAD $1,500 annual Active Lifestyle Allowance, annual vacation, and company-wide office closures. We prioritize teams and social groups to build community and connections across AbCellera.

About AbCellera

AbCellera is a global company that discovers and develops antibody-based medicines that help people live longer, happier, and more productive lives. We are focused on bringing innovative medicines to patients, both by advancing our internal pipeline of programs and partnering with companies that have novel science or innovative technology.



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