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Research Associate, Analytical

4 months ago

Vancouver, Canada Acuitas Full time

**_Acuitas Therapeutics is a private biotechnology company based in Vancouver, British Columbia, Canada. We are the premier global provider of LNP delivery systems for nucleic acid therapeutics. Acuitas is partnered with multiple international, biotechnology and pharmaceutical partners who are focused on bringing new vaccines and drugs into clinical development and to the marketplace._**

**_ All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or any other status protected by applicable law._**

Job Title: Research Associate, Analytical

YOU: A committed professional with experience in analytical chemistry looking to develop further in an innovative, fast paced biotech environment

US: Leading innovators in the lipid nanoparticle (LNP) field, looking for a talented individual to join our collaborative, passionate, diverse pharmaceutical focused team.

ROLE SUMMARY:
Acuitas Therapeutics is seeking a Research Associate to work in the Analytical Group, reporting to the Director, Analytical. The role holder will be responsible for execution of studies, including physical and chemical characterization of LNP systems, managing and executing analyses, and interpretation/presentation of results.

JOB DESCRIPTION:
Working with the Director, Analytical, the responsibilities would include:

- General laboratory support including preparation of reagents and solutions, laboratory organization, and management of consumables.
- Routine analysis of LNP formulations and components following standard in-house methods including UPLC, LC-MS, DLS, absorbance/fluorescence spectroscopy, electrophoresis, and associated data acquisition software.
- Contribute to the development of new analytical assays, assessment of new analytical technologies, and investigations of specific LNP attributes as required.
- Contribute to the development, optimization and troubleshooting of formulations and manufacturing processes at various scales.
- Participation in technology transfer activities related to manufacturing processes and/or analytical methods.
- Laboratory management duties related to operations and maintenance of the Analytical function.
- Collaborative analytics with other departments including Formulation Development, Process Development, and Pre-Clinical.
- Maintain familiarity with relevant scientific knowledge and advancements.

QUALIFICATIONS AND SKILLS:

- A minimum level of education, training, or experience equivalent to a Bachelor of Science in an appropriate discipline and two (2) years of recent related experience in a research laboratory.
- Excellent bench skills, the ability to master new techniques quickly, and be able to work independently.
- Experience working with lipid nanoparticle formulations including characterization of formulations and raw material components by standard and/or specialized analytical techniques (such as absorption and fluorescence spectrometry or chromatographic separations)

Familiarity with HPLC/UPLC, fluorescence/absorbance spectroscopy, general laboratory/analytical techniques, statistical design of experiments, data modeling, scale-up process development, and/or regulatory aspects of LNP products and raw materials would be an asset.