Research Associate Ii, Chemistry

2 weeks ago

Vancouver, Canada Chinook Therapeutics Full time

**Company**:
Chronic kidney diseases are a severe and growing worldwide problem with a lack of effective treatments often leading to dialysis, transplantation, and high costs to health care systems. Up to 10% of the global population suffers from kidney disease and in the U.S. alone, kidney diseases account for over $130 billion in annual costs.

At Chinook Therapeutics our purpose is to discover and develop precision therapies to preserve kidney function and make dialysis and transplant unnecessary for people living with kidney disease. We strive for excellence in all we do and think big in our innovation; our highest priority is to do the right thing for patients while working together and having a whole lot of fun

**_We seek applicants from all backgrounds to ensure we get the best, most creative talent on our team. We are building a diverse and inclusive workforce -come and be a part of our growth._**

**Position**:
**Responsibilities include**:

- Design, research, synthesize, purify, analyze and characterize small molecule compounds using modern, multi-step, synthetic organic chemistry techniques
- Participate and present data in interdisciplinary research and development projects working with chemists, biologists, pharmacologists and DMPK colleagues
- Maintain a safe lab environment and work within defined safe laboratory practices

**Location**:_Chinook has offices located in Seattle WA, Oakland CA, and Vancouver BC_
- This is an on-site position located in Chinook's Vancouver BC office

**Education, Experience, and Skills**:
**Required**:

- M.Sc. degree from a recognized university, specializing in small-molecule synthetic organic chemistry with methodology development or total synthesis experience
- B.Sc. degree with 2 plus years’ experience in synthetic / medicinal organic chemistry, ideally in a biopharmaceutical environment
- Excellent understanding and technical capabilities in synthetic organic chemistry techniques and procedures, including:
- 100 g scale reaction synthesis
- Multi-step organic synthesis (3-10 steps) and synthetic route optimization
- Purification of novel small molecules by flash chromatography, HPLC and crystallization
- Characterization of novel small molecules with LCMS, 1D and 2D NMR
- Modern synthetic organic methodology development experience as demonstrated by publication record in major peer-reviewed journals

**Preferred**:

- 2 plus years’ experience in synthetic / medicinal organic chemistry, ideally in a biopharmaceutical environment
- Experience in using online chemical search tools, such as SciFinder
- A strong team player with a passion for science and drug discovery
- Effective and strong communication skills, with the ability to present, explain and summarize scientific research and research progress
- Positive attitude and high personal and ethical standards

**Salary Range**:$86,000 - $100,000

**Benefits**:

- Paid parental leave
- Vacation and Sick time
- Living organ donor leave
- Volunteer time off
- 15 Paid Holidays
- Hybrid Work
- Flexible scheduling
- Healthcare plans
- Retirement Matching
- Financial wellness programs
- Employee assistance programs (EAPs)
- Internal learning & development courses
- Chinook is an Equal Opportunity Employer, and we prohibit discrimination or harassment of any kind. We are committed to fostering an environment where ALL people are welcome and supported. _We cultivate a culture of inclusion for all employees that respects their individual strengths, views, and experiences. We believe that our differences enable us to be a better team - one that makes better decisions, drives innovation, and delivers better business results. _Creativity and innovation flourish in an environment of openness, inclusion, and mutual respect._

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