Computational Biologist, Genome Sciences Centre

6 months ago

Vancouver, Canada PHSA Full time

**Computational Biologist, Genome Sciences Centre**

BC Cancer

Vancouver, BC

About the GSC

Canada’s Michael Smith Genome Sciences Centre (GSC)

Today’s Research. Tomorrow’s Medicine.

The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases.

Among the world’s first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.

Among the GSC’s most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.

By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.

Computational Biologist, Clinical

Canada’s Michael Smith Genome Sciences Centre (GSC) is a state-of-the-art, large scale, high throughput, clinically accredited genomics and bioinformatics facility. If you have a Bachelor of Applied Science or a Bachelor of Science in biological science or computer science, as well as an interest in programming and human health, this is your opportunity to become involved in a team working with cutting-edge technology as a Clinical Computational Biologist.

As a Computational Biologist, you will perform bioinformatics analyses and contribute to software development related to the operation of a large-scale clinical sequencing facility. The position is anchored within a team of exceptional scientists, computational biologists and programmers, which collaborate directly on the development of robust, cost efficient and competitive processes for new targeted and precision medicine analytical pipelines. Your work will help to save lives and contribute to a world free from the fear of cancer.

By working within the GSCs bioinformatics facility, the successful applicant will develop close relationships with world-renown computational and genome science technologists, cancer researchers and medical scientists; have access to one of the most robust computational and next generation genome sequencing technology facilities in Canada, all while living in one of the most beautiful, diverse and eclectic cities in the world.

**What you’ll do**
- Contribute to the design, development, implementation, validation, running, and maintenance of clinical bioinformatics pipelines and related databases.
- Contribute to incorporation of third-party software into clinical bioinformatics pipelines, including:

- determining optimal parameters for the chosen software
- developing interfaces to integrate the chosen software and
- validating integration of the chosen software.
- Participate in the development of novel software solutions, as directed by the Assistant Bioinformatics Coordinator or Clinical Bioinformatics Coordinator.
- Participate in peer code review.
- Contribute to writing and updating official procedures and other documentation related to clinical bioinformatics pipelines.

**What you bring**

Qualifications:

- Graduation from a recognized Bachelor of Applied Science or Bachelor of Science Program in either Biological Sciences or Computer Science.
- Two (2) year’s of recent related experience or an equivalent combination of education, training and experience acceptable to the GSC Group Leaders.

You have:

- Skill with Python or other similar high level languages.
- Functional knowledge of distributed version control systems, such as Git.
- Demonstrated ability in R or other similar statistical programming languages.
- Familiarity with relational databases, such as PostgreSQL, and with ORMs
- Ability to program and run analyses in a production environment
- Commitment to upholding the shared responsibility of creating lasting and meaningful reconciliation in Canada as per TRC (2015) and BC's Declaration on the Rights of Indigenous Peoples Act (2019).
- Knowledge of social, economic, political and historical realities impacting indigenous communities and familiarity with Indigenous Cultural Safety and anti-racism and accompanying reports (BC DRIPA, TRC, etc.).

**What we bring**

Every PHSA employee enables the best possible patient care for our patients and their families. Whether you are providing direct care, conducting research, or making it possible for others to do their work, you impact the lives of British Columbians today and in t

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