Research Scientist

2 weeks ago

Vancouver, Canada UBC Full time

Staff - Non Union

Job Category
M&P - AAPS

Job Profile
AAPS Salaried - Research and Facilitation, Level A

Job Title
Research Scientist

Department
Kobor Laboratory | Centre for Molecular Medicine and Therapeutics | Faculty of Medicine

Compensation Range
$5,209.17 - $7,485.33 CAD Monthly

The Compensation Range is the span between the minimum and maximum base salary for a position. The midpoint of the range is approximately halfway between the minimum and the maximum and represents an employee that possesses full job knowledge, qualifications and experience for the position. In the normal course, employees will be hired, transferred or promoted between the minimum and midpoint of the salary range for a job.

Posting End Date
March 29, 2024

**Note**: Applications will be accepted until 11:59 PM on the day prior to the Posting End Date above.

Job End Date

Jun 2, 2025

This position is expected to be filled by promotion/reassignment and is included here to inform you of its vacancy at the University.

At UBC, we believe that attracting and sustaining a diverse workforce is key to the successful pursuit of excellence in research, innovation, and learning for all faculty, staff and students. Our commitment to employment equity helps achieve inclusion and fairness, brings rich diversity to UBC as a workplace, and creates the necessary conditions for a rewarding career.

Job Summary

The Kobor Lab is seeking a highly motivated and ambitious individual to work as a research scientist on various projects related to understanding the causes and consequences of variation in epigenetic marks across human populations, and using animal-based model studies. The successful applicant will be responsible for leading and contributing to a number of existing funded projects. These include population cohort studies that focus on the genomic embedding of early-life experiences in relationship to development and health across the lifespan, as well as cell-based simulation studies examining molecular marks associated with exposure to environmental factors. This work involves the generation and acquisition of high-dimension datasets for genotyping, DNA methylation, chromatin conformation and mRNA expression and their integrative analysis with phenotype and environmental exposures.

The ideal applicant will possess a curiosity and passion for science, a talent for independent and team-based research, knowledge of statistical genomics and/or epigenetics / gene regulation, and extensive experience with high-throughput data generation and bioinformatics.

Organizational Status
This position reports to the lead Principal Investigator Dr. Michael Kobor (Medical Genetics), and works in conjunction with other investigators and research personnel within the Centre for Molecular Medicine and Therapeutics (CMMT) and BC Children's Hospital Research Institute (BCCHRI). The position may provide occasional training and supervision of technicians and students, and interact with local, national, and international collaborators on a regular basis.

Work Performed

Designs, performs, and evaluates data quality of bench-based high-throughput microarrays (DNA methylation, genome-wide SNP typing) studies
Consults with collaborators for best-practices with sample collections and preparations to ensure success of array-based experiments
Reviews current literature to propose, develop, and establish next-generation sequencing-based studies (RRBS, ATAC-Seq, RNA-Seq, single cell) pertinent to epigenomic analyses using advanced technologies
Performs statistical and bioinformatics analyses of high-throughput epigenomics, genotyping, and sequencing data to facilitate the interpretation of associations between molecular data with environment, stress and disease in humans and cell-based studies
Participates in planning and execution of research projects, alone and in teams
Participates in meetings and phone/video conferences as project lead for multiple collaborations with local, national, and international groups on diverse projects related to children's mental and physical health, and works with academics, clinical and community practitioners, and other professionals from multiple disciplines
Presents results to collaborators and the broader scientific community
Contributes to ongoing strategic planning for the ongoing bioinformatics analysis needs of the lab; works with principal investigator to identify funding opportunities; develops ideas into grant proposals
Contributes to writing scientific manuscripts
Performs other administrative and related duties in the lab

Consequence of Error/Judgement
The incumbent will make important decisions affecting the productivity of the lab. Poor judgment could result in loss of experimental data and delay in conducting research, which could impact collaborations, publications, and future funding. Studies may be jeopardized if not conducted according to ethical requirements as laid out by the University and by regulato

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