Research Scientist, Process Development
6 months ago
For Current Gilead Employees and Contractors:
At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer - working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.
Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact.
We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.
**Job Description**:
Research Scientist - Process Development - Edmonton, Alberta
Gilead has pursued and achieved breakthroughs in medicine for more than three decades, with the goal of creating a better, healthier world for all people. We have commercialized more than 25 innovative medicines, helping to transform treatment for people living with HIV, viral hepatitis, cancer and other life-threatening diseases. Through our ongoing bold and transformative science, we’re driving innovations that have the potential to become the next generation of life-changing medicines.
Gilead Sciences in Edmonton, Alberta, Canada, has opportunities for highly motivated scientists to join various groups in the Pharmaceutical Development & Manufacturing (PDM) organization. With your commitment and drive, you will be part of a cross-functional drug development team whose goal is to develop curative medicines helping millions of people live healthier, more fulfilling lives. With state-of-the-art research facilities and a team of experienced scientists who are passionate about developing drugs, the Process Development and Analytical Operations groups at Gilead empower every chemist to take part in the act of innovation.
Job Responsibilities:
- Responsible for developing chemical processes for the manufacturing of drug substances- Demonstrates technical knowledge, scientific creativity, and collaboration skills in the development and execution of research for the preparation of novel chemical substances- Plans, executes and analyzes laboratory experimentation to advance the knowledge of production and quality attributes of drug substances- Proposes alternative chemistry, including new route selection and step optimization- Provides regular updates to supervision and proposes future research directions- In collaboration with senior scientists, develops project strategy for manufacturing of drug substances to support clinical studies and commercialization- May be responsible for the day to day management of project team members and research assignments, including designing and interpreting of experimentation- Prepares and reviews technical documents including research reports, process development reports, and documentation for the manufacturing of chemical substances e.g. Master Batch Records (MBRs)- Collaborates across functional areas including analytical chemistry, quality assurance, and manufacturing to accomplish project goals- Provides technical support for manufacturing processes performed under cGMP in laboratory manufacturing and large-scale manufacturing operations- Ensures that all experimentation is carried out in accordance with appropriate standard operating procedures (SOPs), maintaining quality, safety, and environmental standards
Knowledge, Experience and Skills:
- PhD in Organic Chemistry (or related discipline) strongly preferred, or MSc/BSc degree with extensive industry experience- Experience in planning and executing multi-step synthesis of organic molecules- Experience scaling up synthetic routes and developing safe processes- Familiarity with purification and analytical techniques, including HPLC, LCMS and NMR- Strong desire to work in multi-disciplinary teams, learn new skills and solve problems- Excellent verbal and written communication skills, and strong interpersonal collaboration skills- Must think critically and creatively and be able to work independently to determine appropriate resources for resolution of problems- Strong organizational and planning skills
For Current Gilead Employees and Contractors:
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