Technician, Operations, Downstream Processing

6 days ago


Charlottetown, Canada Merck Sharp & Dohme Full time

This Technician position is within the Production Department at our Animal Health facility in Charlottetown, Prince Edward Island. The Charlottetown facility manufactures vaccines and biologics used within aquaculture farming.

Leveraging an experienced and innovative team environment, the key technologies at the site are biologics production using fermentation, tangential flow filtration, chromatography, cell culture platforms, and sterile filling.

The Charlottetown facility is part of our global Animal Health Manufacturing Division network and is a key contributor to the manufacturing of animal health products. Working within one of the manufacturing operations teams you will be expected to be able to work independently and as part of the team to contribute to the daily completion and schedule adherence of production activities.

The Nucleic Acid Vaccine manufacturing operation is made up of teams that carry out the production activities for the preparation of equipment, buffers and media components, fermentation of bacteria, downstream processing of plasmid DNA and blending of the final vaccines prior to sterile filling.

The position requires someone who can demonstrate a good attention to detail and achieve a consistent error-free execution of daily job responsibilities, be able to complete documentation using Good Documentation Practices and be able to identify opportunities for process improvement and employ basic problem-solving skills.

**Education Minimum Requirement**:
High School diploma or equivalent

**Required Experience and Skills**:

- One or more years of experience working in a Good Manufacturing Practices environment.
- Proficient oral and written communication skills.
- Able to follow/comply with Manufacturing Directions, Standard Operating Procedures, Company/Corporate/Regulatory Policies.
- Ability to demonstrates basic skills in effective time management to meet given deadlines.
- Able to work effectively with team members and show initiative to support others on the team when needed.
- Proficient computer skills including MS Word and MS Excel.

**Preferred Education, Experience and Skills**:

- A 2-year college diploma in a Science related discipline
- Experience working in a Good Manufacturing Practices environment.
- Experience with one or more of the following technologies/processes: Bacterial fermentation, Tangential Flow Filtration or Chromatography,
- Experience performing investigations and assisting in deviations.
- A good understanding of aseptic processes used in manufacturing.
- Experience using quality improvement tools and continuous improvement processes and site quality metrics.
- Intermediate mathematical skills preferred.

**Other Requirements and Information**:

- Must be able to work 12-hour shifts (12-hour daytime shifts, 3-4 days/week including some weekends) and overtime as required.
- Must be able to wear clean room garments and remain in clean room area for up to 3 hours at a time.
- Required to assist in disinfection procedures involving hazardous chemicals requiring the use of a respirator.
- Must be able to lift, move and maneuver small-medium sized equipment - up to 25lbs.
- Requires ability to stand for long periods of time.
- Requires frequent ladder or stair climbing.
- Must be able to read, write, understand, and comply with appropriate standard operating procedures.

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.

**Secondary** Language(s) Job Description**:
Ce poste de technicien (ne) se trouve au sein du département de production de notre installation de santé animale à Charlottetown, Île-du-Prince-Édouard. L'installation de Charlottetown fabrique des vaccins et des produits biologiques utilisés dans l'aquaculture.

En tirant parti d'un environnement d'équipe expérimenté et innovant, les technologies clés sur le site sont la production de produits biologiques utilisant la fermentation, la filtration tangentielle, la chromatographie, les plateformes de culture cellulaire et le remplissage stérile.

L'installation de Charlottetown fait partie de notre réseau mondial de la division de fabrication de santé animale et est un contributeur clé à la fabrication de produits de santé animale. Travaillant au sein de l'une des équipes d'opérations de fabrication, vous devrez être capable de travailler de manière autonome et en équipe pour contribuer à l'achèvement quotidien et au respect du calendrier des activités de production.

L'opération de fabrication de vaccins à acide nucléique est composée d'équipes qui réalisent les activités de productio



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