Research Associate, Process Development

2 weeks ago


Montréal, Canada 35Pharma Inc. Full time

**35Phama** is a biopharmaceutical company that designs and develops innovative therapies for life-threatening lung diseases, musculoskeletal and metabolic disorders. We believe in connecting rigorous science with our innate sense of urgency to rapidly generate breakthrough therapies for patients in need of a better quality of life. Our highly skilled team of drug developers and business builders have a proven track record of advancing complex biologics from discovery to clinical trials. Our R&D facilities are located in the heart of Montreal, Canada, and include laboratory spaces for manufacturing development and preclinical research that reinforce our mission to serve patients in need.

**Role**:
This is a full-time position reporting to the Associate Director of Process Development and is based in **Montreal, QC, Canada**.

**Functions and responsibilities**:

- Perform mammalian cell culture activities such as cell maintenance, transfection for transient expression as well as preparation of stable expression pools using CHO cell lines.
- Perform routine analyses (CE-SDS, SDS-PAGE, ELISA, HPLC).
- Responsible for the analysis and documentation of experimental data (electronic laboratory notebook and files).
- Prepare protocols and reports on experiments performed.
- Responsible for the maintenance of laboratory equipment.
- Provide technical and scientific support during the development process.
- Participate in technology transfer activities.
- Use a quality-by-design (QbD) approach during all process development phases.

**Qualifications**:

- At least a Bachelor of Science (B.Sc.) degree in biochemistry, biotechnology, life sciences or equivalent.
- A minimum of 2 years of experience in process development and/or manufacture of recombinant proteins or relevant experience in biotechnology or biopharmaceutical industry.
- Experience in purification of recombinant proteins (chromatography, TFF)
- Experience in mammalian cell culture and recombinant protein expression systems.
- Meticulous laboratory practice with good aseptic technique.
- Knowledge of downstream process technologies and protein purification.
- Ability to conduct experiments independently.
- Ability to work in multifunctional teams and in a dynamic environment.
- Experience in problem solving.
- Knowledge of Good Manufacturing Practice (GMP) is an asset.
- Effective communicator in writing and speaking.

**Job Types**: Full-time, Permanent

**Benefits**:

- Commuter benefits
- Company events
- Dental care
- Disability insurance
- Employee assistance program
- Extended health care
- Flexible schedule
- Life insurance
- Paid time off
- Vision care
- Wellness program

Schedule:

- Monday to Friday

**Experience**:

- process development of recombinant proteins: 2 years (required)

Work Location: In person


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