Head of Facilities

2 months ago

Hamilton, Canada Fusion Pharmaceuticals US Inc Full time

Fusion Pharmaceuticals, a member of the AstraZeneca Group, is a clinical-stage oncology company focused on developing next-generation radioconjugates (RCs) as precision medicines. Fusion connects alpha particle emitting isotopes to various targeting molecules to selectively deliver the alpha emitting payloads to tumors. Fusion’s clinical portfolio includes: FPI-2265 targeting prostate specific membrane antigen (PSMA) for metastatic castration resistant prostate cancer currently in a Phase 2 trial; FPI-1434 targeting insulin-like growth factor 1 receptor currently in a Phase 1 trial; FPI-2059, a small molecule targeting neurotensin receptor 1 (NTSR1), currently in a Phase 1 trial; and FPI-2068, a bispecific IgG-based EGFR-cMET targeted radioconjugate currently in a Phase 1 trial. In addition, Fusion is pursuing combination programs between RCs and DNA Damage Response Inhibitors (DDRis) and immune-oncology agents. Fusion has a fully operational Good Manufacturing Practice (GMP) compliant state-of-the-art radiopharmaceutical manufacturing facility to meet supply demand for Fusion's growing pipeline of RCs.


The Head of Facilities is a multifunctional position responsible for all aspects of site operations which requires a background in facility maintenance, laboratory operations, facility project planning, move logistics and environmental health and safety. A background with a pharmaceutical manufacturing (GMP) facility (production, clean rooms, shipping and receiving etc) would be preferable. The candidate must have experience developing and executing strategic plans in Facilities which are aligned with Fusion Pharmaceuticals operational needs. Must be able to build efficient teams and foster strong professional relationships with scientific staff, employees, and numerous service providers to ensure smooth operations of the business and scientific laboratories. This position is located in our Hamilton, Ontario office and reports into our Chief Legal Officer.

Responsibilities

Facility Management

  • Oversee the daily operations, maintenance, and safety of company facilities, including manufacturing, laboratories and offices areas.
  • Manage and oversee capital projects such as renovations and facility expansions from conception to completion.
  • Work with internal teams to ensure compliance with Health Canada, FDA and GMP regulatory requirements.
  • Oversight of routine facility maintenance, upkeep, and repair of building systems including HVAC, MEP and various installed distribution systems and other systems specific to Fusion’s manufacturing operations.
  • Manage external vendors and services providers from contract negotiation to performance review.
  • Plan, execute, and maintain administrative processes and records related to critical systems such as security, environmental controls, and temperature alarm systems.
  • Monitor critical systems and provide 24-hour on-call support in case of system failure.
  • Maintain awareness of health and safety issues and effectively manage safety consultants.


Environmental Health and Safety

  • Provide EHS support to, and collaborates with, employees within the organization, with a focus on engagement through compliance, OSHA and continuous improvement efforts.
  • Develop, modify, implement, and maintain EHS policies and procedures to achieve compliance and improve EHS performance.
  • Manage company training needs and develop & maintain processes to ensure compliance.
  • Act as an agent of positive change to build an effective EHS culture through accountability, processes, and training.
  • Evaluate the impact of new or changed regulations, standards, and policies on operations and initiate and oversee updates to EHS policies, programs and procedures in proactive manner.

Qualifications:

  • Bachelor’s degree in Facilities Management, Engineering, or a related field required.
  • Minimum 10 years of progressive facilities management experience including oversight of lab environment.
  • Biotech / life sciences experience required.
  • Strong background in facility operations and GMP regulations – both manufacturing and laboratory operations.
  • Proven track record in managing capital projects and facility expansions.
  • Previous experience with issue tracking systems.
  • Highly proficient in Microsoft Office (Excel, Word, Outlook, Teams and PowerPoint).
  • Demonstrate clear and professional verbal and written communication.
  • Solid project management, planning, organization, and time management skills.


All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.

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