Scientist - Process Development

6 days ago


Edmonton Alberta, Edmonton region, Canada eTeam Full time

Job Title: Research Scientist – Process Development

Location: Edmonton, Alberta

Onsite


Job Responsibilities:

• Responsible for developing chemical processes for the manufacturing of drug substances

• Demonstrates technical knowledge, scientific creativity, and collaboration skills in the development and execution of research for the preparation of novel chemical substances

• Plans, executes and analyzes laboratory experimentation to advance the knowledge of production and quality attributes of drug substances

• Proposes alternative chemistry, including new route selection and step optimization

• Provides regular updates to supervision and proposes future research directions

• In collaboration with senior scientists, develops project strategy for manufacturing of drug substances to support clinical studies and commercialization

• May be responsible for the day to day management of project team members and research assignments, including designing and interpreting of experimentation

• Prepares and reviews technical documents including research reports, process development reports, and documentation for the manufacturing of chemical substances e.g. Master Batch Records (MBRs)

• Collaborates across functional areas including analytical chemistry, quality assurance, and manufacturing to accomplish project goals

• Provides technical support for manufacturing processes performed under cGMP in laboratory manufacturing and large-scale manufacturing operations

• Ensures that all experimentation is carried out in accordance with appropriate standard operating procedures (SOPs), maintaining quality, safety, and environmental standards


Knowledge, Experience and Skills:

• PhD in Organic Chemistry (or related discipline) strongly preferred, or MSc/BSc degree with extensive industry experience

• Experience in planning and executing multi-step synthesis of organic molecules

• Experience scaling up synthetic routes and developing safe processes

• Familiarity with purification and analytical techniques, including HPLC, LCMS and NMR

• Strong desire to work in multi-disciplinary teams, learn new skills and solve problems

• Excellent verbal and written communication skills, and strong interpersonal collaboration skills

• Must think critically and creatively and be able to work independently to determine appropriate resources for resolution of problems

• Strong organizational and planning skills



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