Scientist
3 days ago
12 month contract starting in January
Fully on-site in North York
Pay range: $35-50/hr
Must-Haves
- Hands-on experience with molecular engineering tools, including molecular cloning, nucleic acid analysis, and protein expression.
- Demonstrated experience in mammalian cell culture (e.g., SF9, CHO, Vero).
- Proficiency in analytical techniques, such as virus titration assays, FACS, protein assays, SDS-PAGE, Western blot, and HPLC.
- Knowledge and experience in bioprocessing methods and process scale-up.
- Proficiency in Microsoft Office Suite (Word, Excel, PowerPoint).
- Strong organizational and leadership skills, with attention to detail and accountability.
- Excellent communication and interpersonal skills, with a team-oriented mindset.
Preferred Qualifications
- Experience with statistical analysis software (JMP, GraphPad Prism).
- Educational background: PhD with 1+ years’ experience or MSc with 3+ years’ experience in Biochemical Engineering, Life Sciences, Biology, Immunology, or Biochemistry.
Responsibilities
- Collaborate with the Global Antigen Design team to screen vaccine candidates, design molecular constructs, and conduct genetic stability testing.
- Lead and support upstream process optimization, working with technologies like AMBR high-throughput bioreactors and small-to-pilot scale bioreactors.
- Perform or coordinate analytical testing (e.g., viral titration, FACS, protein assays) to support process development.
- Conduct statistical data analysis, prepare technical reports, and present findings to stakeholders.
- Contribute to process characterization studies using Design of Experiments (DoE) methodology and facilitate tech transfer to clinical manufacturing teams.
- Support digital initiatives, such as AI integration, and ensure compliance with GxP quality standards, documentation, and HSE policies.
Summary
Insight Global is seeking a Vaccine Drug Substance Development Scientist to join our Global Bioprocess Development (GBD) team, specifically within the Vaccine Drug Substance Development (VDSD) department. This role focuses on the process development and scale-up of novel vaccine candidates through advanced molecular engineering, viral cell culture, bacterial fermentation, and supportive analytical techniques. The ideal candidate will collaborate across teams to lead upstream and downstream processes, optimizing methods up to a 200L scale. This is an excellent opportunity for a motivated scientist to contribute to impactful vaccine projects while ensuring compliance with industry regulations.
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