Lead, Biotherapeutic Analytics

2 weeks ago

Vancouver, British Columbia, Canada AbCellera Biologics Full time

How you might spend your days:

  • Leading and managing antibody and other protein analytical characterization activities supporting program advancement and platform development
  • Prioritizing and planning the execution of characterization requests, as well as improving request management and communication systems
  • Coaching, mentoring, and developing talent within a growing and dynamic team
  • Stay scientifically current, driving innovation, and implementing new technologies and workflows to expand and automate antibody characterization capabilities, including leveraging data science and machine learning
  • Leading the development and automation of early formulation, developability, and stability assessment workflows to drive lead selection
  • Leading the development and implementation of standard operating procedures
  • Liaising with partners and communicating project updates and deliverables
  • Driving strong collaboration and communication across teams in early Discovery, Bioinformatics, Protein Engineering, Translational, and CMC

We'd love to hear from you if:

  • You are a builder who is passionate about developing innovative approaches to the discovery and development of biotherapeutics
  • You are strongly selfmotivated and can identify project needs and implement solutions
  • You take pride in investing time to mentor team members to enhance their skills and drive career development and high performance
  • You are an outstanding communicator and teammate

Required qualifications and experience:

  • A PhD in Biochemistry, Biophysics, Biotechnology, Structural Biology or related field with an additional 10+ years of experience, with at least half of that time being in the biopharma or biotechnology industries.
  • Demonstrated expertise in detailed analytical characterization of antibodies or other protein therapeutics using mass spectrometry, analytical chromatography, capillary electrophoresis, isoelectric focusing, light scattering, or related techniques
  • In depth understanding of antibody sequence and structure as well as common modifications and degradation mechanisms
  • Experience with antibody stability and developability assessment including both high throughput screening and detailed interrogation of physical and chemical stability risks
  • Track record of successful leadership and management, with a focus on developing talent
  • Excellent creativity, decisionmaking, and troubleshooting skills.
  • Impeccable attention to detail, excellent communication, documentation and technical writing skills
  • Great interpersonal skills with the ability to work collaboratively as a member of a crossfunctional team
  • Experience working in a CMC organization, or familiarity with regulatory issues related to biologics quality would be an advantage
  • Familiarity with antibody binding and other mechanistic data from SPR or related technologies would be an advantage
  • Experience with automation would be an asset

What we offer:

A generous compensation package including an equity stake in AbCellera's success. Our headquarters are nestled in the heart of Vancouver, Canada - we'll support you and your family in every way we can to relocate if you haven't had the joy of living in this beautiful area

About AbCellera:

At AbCellera, we find the next generation of therapeutic antibodies.

To succeed, we have created innovative solutions at every step - custom antigen preparation and immunizations, microfluidics, high-throughput imaging, genomics, computation, machine learning and laboratory automation - leaving no stone unturned and revolutionizing how scientists can explore natural antibody diversity and the scale at which they can do it.

You'll join a diverse and multi-disciplinary team of biologists, biochemists, engineers, bioinformaticians, computer scientists and physicists - all working together to bring better therapies to patients.

This is life-changing research and you could be a part of it.

We're a growing company with state-of-the-art discovery tools and the drive to be the best in the industry. This isn't just about having the best technology. We know we need a world-class team of innovators working together to solve the toughest problems. We look for people with drive and energy. Idealists. People we love and people we trust. This may be unconventional, but it is the key to our success. We're looking for someone like you to support and organize our efforts along the way.

To apply:

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