Research Associate in 3D Human Tissue Bioprinting for Modeling Neurodegenerative Disorders
4 weeks ago
Vancouver, British Columbia, Canada
University of British Columbia
Full-time
$95,000 Contract
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JOB CATEGORY
Faculty Non Bargaining
JOB TITLE
Research Associate in 3D Human Tissue Bioprinting for Modeling Neurodegenerative
Disorders
DEPARTMENT
Nygaard Laboratory Division of Neurology | Department of Medicine | Faculty of
Medicine (Haakon Nygaard)
POSTING END DATE
August 14, 2026
Note: Applications will be accepted until 11:59 PM on the Posting End Date.
JOB END DATE
September 30, 2028
Please note, this is a two (2) year term position, with the possibility of
renewal.
The compensation for this position is $95,00 per annum.
Job Summary
Situated the Djavad Mowafaghian Centre for Brain Health at the University of
British Columbia the Post-Doctoral candidate will develop/design, implement and
publish research studies related the cellular processes associated with
Alzheimer’s disease (AD) and frontotemporal dementia. Specifically, the position
involves maintaining and advancing a robust protocol for 3D bioprinting of iPSC
derived neurons, astrocytes, and microglia to study the pathophysiology of AD
and FTD in a 3D environment. In addition, methods of research including but not
limited to: human induced pluripotent stem cells (hiPSC), cerebral organoids,
CRISPR gene editing, transfections, imaging techniques, electrophysiology and
biochemical/molecular biology techniques. The candidate will have a strong
teaching role for graduate, undergraduate and co-op students.
The position requires a strong research background in neuroscience and
neuroscience techniques including iPSCs generation, differentiation, and
maintenance, tissue culture, and confocal imaging. The candidate must have a
PhD, and at least 2 years of post-doctoral experience in advanced 3D bioprinting
of hiPSC neurons using an extrusion-based bioprinter. The candidate must further
have advanced knowledge of bioink preparations, including those based on
collagen.
Organizational Status
The successful candidate will work under the supervision of Professor Haakon
Nygaard in the department of Neurology in the Faculty of Medicine.
Responsibilities will include, but are not limited to:
* 3D bioprinting of iPSC-derived tissues
* Design and implement research studies and related programs, including planning, managing, producing and analyzing the data. The candidate is expected to lead these efforts.
* Communicate with wet lab scientists in the day-to-day activities including but not limited to the data collection, quality control, data cleaning, data analysis, and presentation.
* Extensive use of induced pluripotent stem cell-derived cell types in experiments
* Histology, biochemical analysis, -omics, and electrophysiology experiments of iPSC-derived tissues
* Prepare manuscripts and oversee submission
* Lead grant applications in the field of neurosciences
* Maintain safe and clean lab spaces used
* Mentor and teach graduate, undergraduate and Co-op students Consequence of Error The position requires research experience, excellent communication skills, tact, judgment, and discretion in working with various senior professionals and collaborating with internal and external agencies. Errors in decision making may compromise the reputation of the PI’s, the research team, and their collaborators, and funding. Requirements PhD in the field of neuroscience or related field, and at least 2 years of post-doctoral training in hiPSC 3D extrusion-based bioprinting, Proven skills using hiPSCs studying the pathophysiology of neurodegenerative or other CNS disorders. Additionally, strong analysis skills, ability to work professionally with colleagues, donors, and staff, and compliance with approved procedures and ethics regulations, publications in the area are an asset.
* 3D bioprinting of iPSC-derived tissues
* Design and implement research studies and related programs, including planning, managing, producing and analyzing the data. The candidate is expected to lead these efforts.
* Communicate with wet lab scientists in the day-to-day activities including but not limited to the data collection, quality control, data cleaning, data analysis, and presentation.
* Extensive use of induced pluripotent stem cell-derived cell types in experiments
* Histology, biochemical analysis, -omics, and electrophysiology experiments of iPSC-derived tissues
* Prepare manuscripts and oversee submission
* Lead grant applications in the field of neurosciences
* Maintain safe and clean lab spaces used
* Mentor and teach graduate, undergraduate and Co-op students Consequence of Error The position requires research experience, excellent communication skills, tact, judgment, and discretion in working with various senior professionals and collaborating with internal and external agencies. Errors in decision making may compromise the reputation of the PI’s, the research team, and their collaborators, and funding. Requirements PhD in the field of neuroscience or related field, and at least 2 years of post-doctoral training in hiPSC 3D extrusion-based bioprinting, Proven skills using hiPSCs studying the pathophysiology of neurodegenerative or other CNS disorders. Additionally, strong analysis skills, ability to work professionally with colleagues, donors, and staff, and compliance with approved procedures and ethics regulations, publications in the area are an asset.