Research Associate
2 weeks ago
Location: Vancouver, BC
Company: ScopeSys Inc.
Type: Full-time | On-site |
Start Date: November 1, 2025
About ScopeSys
At ScopeSys, we build next-generation imaging platforms for single-particle microscopy, with a focus on therapeutic lipid nanoparticle (LNP) analytics. We are a Biotech start-up, currently based at UBC's Biomedical Engineering incubator space.
We're currently expanding our R&D capacity and are hiring a Research Associate to help develop/ validate surface chemistries for our imaging platform's consumables. We are looking for a recent graduate, with Bachelors of Science (BSc) or Masters (MS) in Chemistry, Biochemistry, Physics, Biomedical Engineering, or related fields.
Your Role
As a Research Associate for assay/consumable development, you'll take ownership of:
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Preparing and validating bioinert surface coatings for LNP applications (anti-fouling thin films).
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Running fluorescence-based assays to test surface reactivity, fouling resistance, and binding specificity.
● Test and optimize their stability during storage, with the goal of achieving long shelf life.
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Supporting design and execution of high-throughput, single-particle assays that underpin our microscopy and biophysics platforms.
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Working closely with R&D scientists to iterate and optimize surface–molecule interaction workflows for both research and customer-facing tools.
What You'll Do
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Fabricate and characterize thin films and/or polymer bushes (e.g., PEG) on glass substrates.
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Test antifouling properties of the coated surfaces against various nanoparticle formulations, using QCM-D, SPR and/or microscopy-based assays.
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Document procedures in a reproducible format (SOPs, batch logs, notebooks).
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Maintain lab organization: reagent preparation, cleanliness, inventory.
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Troubleshoot surface fouling, binding inconsistency, or signal variability of the coated substrates, for a series of nanoparticle formulations.
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Interface with the microscopy team to align surface prep with real-time imaging needs.
What You Bring
Must-Have:
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BSc or MSc in Chemistry, Biochemistry, Physics, Biomedical Engineering, or related.
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Strong hands-on experience in surface functionalization, wet chemistry, or polymer coatings.
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Familiarity with fluorescence microscopy or spectrometry.
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Working knowledge of NHS-amine coupling or protein/nucleic acid labeling techniques.
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Comfortable with fast-paced, iterative environments and minimal supervision.
Nice-to-Have:
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Experience with anti-fouling coatings, e.g., PEG, polyzwitterions, PLL-g-PEG.
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Prior work in biophysics, nanomedicine, biosensors, or academic–industry hybrid labs.
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Familiarity with ImageJ/Fiji, MATLAB, or Python for data analysis.
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Familiarity with SPR or QCM-D surface characterization techniques
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Understanding of optical biosensing, CLiC microscopy, or surface-based single-molecule assays.
What We Offer
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Hands-on training in next-generation biointerface engineering.
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Opportunity to contribute to translational research, product development, and publications.
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Direct mentorship from cross-disciplinary scientists in surface chemistry, microscopy, and nanomedicine.
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Work in a startup-driven environment with the backing of academic innovation.
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Flexible time-off policy, competitive compensation, and potential for long-term growth within the company.
How to Apply
Send an email to with:
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Subject line: Research
Associate
– Your resume
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A short paragraph or cover letter telling us why this role interests you and how your experience fits the role.
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Resume with education, work experience and other relevant information.
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