Senior Scientist, Process Development

At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world's biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.
 

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Job Description
 

Sr Scientist  – Process Development – Edmonton, Alberta

Job Responsibilities:

• Responsible for developing chemical processes for the manufacturing of drug substances

• Demonstrates technical knowledge, scientific creativity, and collaboration skills in the development and execution of research for the preparation of novel chemical substances

• Plans, executes and analyzes laboratory experimentation to advance the knowledge of production and quality attributes of drug substances

• Proposes alternative chemistry, including new route selection and step optimization

• Provides regular updates to supervision and proposes future research directions

• In collaboration with senior scientists, develops project strategy for manufacturing of drug substances to support clinical studies and commercialization

• Responsible for the day to day management of project team members and research assignments, including designing and interpreting of experimentation

• Prepares and reviews technical documents including research reports, process development reports, and documentation for the manufacturing of chemical substances e.g. Master Batch Records (MBRs)

• Collaborates across functional areas including analytical chemistry, quality assurance, and manufacturing to accomplish project goals. Acts as a subject matter expert for cross-functional teams and research personnel

• Provides technical support for manufacturing processes performed under cGMP in laboratory manufacturing and large-scale manufacturing operations

• Ensures that all experimentation is carried out in accordance with appropriate standard operating procedures (SOPs), maintaining quality, safety, and environmental standards

Knowledge, Experience and Skills:

• PhD in Organic Chemistry (or related discipline) and 2+ years of relevant experience minimum required. We prefer a PhD with 2-10 years ideally, level will be commensurate with experience OR

• MSc/BSc degree with extensive industry experience (6-8+ years)

• Experience in planning and executing multi-step synthesis of organic molecules

• Experience scaling up synthetic routes and developing safe processes

• Familiarity with purification and analytical techniques, including HPLC, LCMS and NMR

• Familiarity with pilot plant and/or plant operations, and experience with generating master batch records is an asset

• Familiarity with process validation, regulatory filings and cGMP regulatory guidelines is an asset

• Strong desire to work in multi-disciplinary teams, learn new skills and solve problems

• Excellent verbal and written communication skills, and strong interpersonal collaboration skills

• Must think critically and creatively and be able to work independently to determine appropriate resources for resolution of problems

• Strong organizational and planning skills

• Experience with project and people management is an asset

Please apply via the Internal Career Opportunities portal in Workday.