Research Assistant, Process Development

6 days ago

Vancouver, Canada Acuitas Full time

**_Acuitas Therapeutics is a private biotechnology company based in Vancouver, British Columbia, Canada. We are the premier global provider of LNP delivery systems for nucleic acid therapeutics. Acuitas is partnered with multiple international, biotechnology and pharmaceutical partners who are focused on bringing new vaccines and drugs into clinical development and to the marketplace._**

**_ All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, status as a protected veteran, or any other status protected by applicable law._**

**Position: Research Assistant, Process Development**

Acuitas Therapeutics is seeking a Research Assistant to work in the Process Development group reporting to the Director, Chemistry, Manufacturing and Controls (CMC). The Research Assistant will be responsible for design and execution of studies, including development and characterization of manufacturing processes for lipid nanoparticle systems, supporting the transfer of manufacturing processes to third-party sites (CMOs), managing and executing analyses, as well as interpreting and presenting results.

**Responsibilities**:
Working under the direction of the Director, CMC, the responsibilities would encompass aspects shown below.
- Development, optimization and troubleshooting of formulations and manufacturing processes at various scales.
- Participation in technology transfer activities related to manufacturing processes and/or analytical methods to ensure progress and success of external partner programs.
- Characterization of LNP formulations and components using standard in-house assays and development of new assays or detailed investigations of specific LNP attributes as required.
- Collaborate with other departments including Formulation Development and Analytical to analyze and interpret data.
- Maintain accurate laboratory notes and data files as well as regularly prepare internal reports of their work.
- Laboratory management duties related to operations and maintenance of the Process Development Functions.
- Maintain familiarity with relevant scientific knowledge and advancements.

**Requirements**:

- A minimum level of education, training, and experience equivalent to a Bachelor of Science or MSc in an appropriate discipline with two (2) years of recent related experience in a research laboratory.
- Familiarity with statistical design of experiments, data modeling, tangential flow filtration, scale up process development, GMP experience and/or regulatory aspects of LNP products and raw materials would be an asset.

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