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Research Associate, Clinical Genomics Informatics Vancouver
3 weeks ago
Research Associate, Clinical Genomics Informatics
BC Cancer
Vancouver, BC
Canada's Michael Smith Genome Sciences Centre (GSC) of the BC Cancer Research Institute is a state-of-the-art, large-scale, high-throughput, clinically accredited genomics and bioinformatics facility located in one of the most vibrant and diverse cities in the world.
As a Research Associate within the Centre for Clinical Genomics Informatics team at the GSC, you will play a pivotal role in advancing clinical bioinformatics capabilities by developing, validating, and optimizing workflows and pipelines to support cutting-edge genomic technologies. The Research Associate will report to the Team leader and is anchored within a team of exceptional computational scientists, programmers and clinical researchers, who collaborate directly on the development and maintenance of robust, cost efficient, and competitive clinical genomics pipelines.
This is an opportunity to work with highly motivated colleagues in a science-oriented, creative and dynamic environment. We offer a competitive salary, excellent benefits and significant career development opportunities.
This position is initially funded for two years.
About the GSC
Canada's Michael Smith Genome Sciences Centre (GSC) Today's Research. Tomorrow's Medicine.
The GSC is a department of the BC Cancer Research Institute and a high-throughput genome sequencing facility. We are leaders in genomics, proteomics and bioinformatics in pursuit of novel treatment strategies for cancers and other diseases. Among the world's first genome centres to be established within a cancer clinic, for more than two decades our scientists and innovators have been designing and deploying cutting-edge technologies to benefit health and advance clinical research.
Among the GSC's most significant accomplishments are the first publication to demonstrate the use of whole-genome sequencing to inform cancer treatment planning, the first published sequence of the SARS coronavirus genome and major contributions to the first physical map of the human genome as part of the Human Genome Project.
By joining the GSC you will become part of an exceptional and diverse team of scientists, clinicians, experts and professionals operating at the leading edge of clinical research. We look for people who share our core values—science, timeliness, respect—to join us on our mission to use genome science for the betterment of health and society.
What you'll do
Propose experimental hypotheses for research and designs experimental questions and protocols in consultation with the Principal Investigator.
Develop new laboratory methods and modifies existing procedures to facilitate research projects.
Collect, record, analyze, validate, interpret and organize experimental and research data and communicate scientific findings to Principal Investigator. Recommend research direction based on preliminary findings in consultation with the Principal Investigator.
Conduct regular literature reviews relating to research areas. Contribute intellectual and scientific input to manuscripts for publications. Present research findings at national and/or international conferences.
Facilitate constructive and collaborative relationships with both the Principal Investigator and internal and external research partners.
**Key Accountabilities**:
Developing clinical bioinformatics workflows for new projects that require quick turnarounds and/or reproducible results and, where relevant, containerizing them.
Analyzing clinical sequencing data from technology development experiments in the lab, summarizing results and formally presenting findings in internal meetings and discussions, including at local, and national meetings.
Supporting technological advances and providing recommendations to wet and dry lab production groups on new technology and workflow optimizations based on comparative analyses, often with custom bioinformatics tools and workflows.
Facilitating the transfer of novel analysis pipelines and technologies into production, such as writing clinical validation documents, drafting Standard Operating Procedures, training production staff, and assisting with troubleshooting exercises.
Training designated members of the clinical bioinformatics group in new or optimized analysis workflows. Writes or revises protocols accordingly.
Identify processes/procedures that can improve and optimize the clinical validation process.
Review data to identify opportunities to offer new or improved assays.
Identify and pursues opportunities to publish in peer reviewed journals to contribute to the broader community.
Perform other technical functions related to the Bioinformatics groups of the GSC.
What you bring
**Qualifications**:
A level of experience, training and education equivalent to a Ph.D. in a related scientific field.
Three (3) years of recent, relevant post-doctoral research experience.
**You have**:
Proven expertise with Python and/or other similar high-level la
