Medical Evidence Lead Bbu Early Assets and Implementation Projects

At AstraZeneca, we pride ourselves on crafting a collaborative culture that champions knowledge-sharing, daring thinking, and innovation - ultimately providing employees with the opportunity to work across teams, functions and even the globe.

Recognizing the importance of individualized flexibility, our ways of working allow employees to balance personal and work commitments while ensuring we continue to build a strong culture of collaboration and partnership by engaging face-to-face in our offices 3 days a week. Our head office and BlueSky Hub in downtown Toronto are purposely crafted with collaboration in mind, providing space where teams can come together to strategize, brainstorm, and connect on key projects.

Our dedication to sustainability is also central to our culture and part of what makes AstraZeneca is an excellent place to work. We know the health of people, the planet and our business are interconnected which is why we’re taking bold actions to address some of the biggest challenges of our time, from climate change to access to healthcare and disease prevention.

**Position Summary**:
**Responsibilities**:

- Plan and deliver observational research and Real World Evidence (RWE) studies in the assigned therapy areas in Canada
- Lead the development and execution of comprehensive evidence plans for both pre-launch and launched products to address full breadth of internal and external partner needs
- Identify, establish, and strengthen data partnerships with healthcare providers, academic organizations, data vendors, and health systems to enhance the breadth and depth of evidence generation opportunities across the AZ portfolio.
- Lead the evaluation of health care transformation and implementation science initiatives, including developing and implementing evaluation frameworks for health system interventions, programs, or policies, and disseminating actionable insights to key stakeholders.
- Interpret evaluation findings, develop performance measures and targets to assess program effectiveness, and support the translation of evidence into clinical practice and measuring impact on patient and health system outcomes.
- Drive use of advanced biostatistics and sophisticated data analytics throughout all stages of research, ensuring rigorous study design and robust interpretation of data using varied healthcare databases.
- Collaborate with key external experts, including academic-clinical investigators, health outcomes researchers, and contract research organizations (CROs).
- Liaise with global counterparts for all evidence generating activities and lead the review and approval process for local studies at AstraZeneca Canada
- Ensure the timely achievement of project-specific breakthroughs and dissemination of scientific publications (e.g., conference presentations, peer-reviewed journal manuscripts)
- Develop and handle communication and knowledge translation plan for all evidence generating activities and ensure presentation of study results to appropriate internal and external partners (e.g., HTA meetings)
- Supervise site start-up activities such as ethics submission, informed consent review, development and finalization of research study agreements and follow-up and maintenance of all study related activities, if required, in accordance with AstraZeneca and international regulatory requirements.
- Develop study budget, timelines, and resources and ensure internal tracking systems are appropriately updated
- Complete feasibility assessments for Global Non-Interventional Studies and provide in-house epidemiology, statistics, and observational research methodology expertise to cross-functional partners.
- Prepare, review, and maintain study documents in accordance with external guidelines and AstraZeneca SOPs.

**Qualifications**:

- Master’s degree or PhD in epidemiology, health services/systems, biostatistics, implementation science, program evaluation, or a related discipline.
- Experience in identifying and building collaborative data partnerships with academic institutions, health systems, data custodians, or technology companies to expand research capabilities.
- Demonstrated expertise in implementation science, including the design and scaling of evidence-based interventions and developing program evaluation frameworks, in real-world healthcare settings.
- Understanding of implementation science frameworks, theories, and methods.
- In-depth understanding and hands-on experience in biostatistics and sophisticated data analytics, including proficiency with large healthcare databases and statistical programming tools.
- Strong track record in generating, synthesizing, and communicating significant and actionable evidence that supports clinical, regulatory, and business decision-making.
- Excellent knowledge of observational study methodology (design and interpretation) and externally sponsored research (including clinical and pre-clinical research).
- Excellent interpersonal, verbal, and wri