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Research Associate, Chemistry

2 weeks ago

SaintLaurent, Canada NuChem Full time

NuChem Sciences, a Sygnature Discovery business is a world-leading integrated drug discovery Contract Research Organisation based in the UK and Canada with its headquarters in Nottingham and additional facilities in Alderley Park, Macclesfield, Glasgow, Montreal and Quebec City. Its staff of over 1,000, which includes 900 scientists, partners with global pharma, biotech and NFP organisations.

**RESPONSIBILITIES**:

- Utilize cutting-edge synthetic methodologies and techniques to design and execute efficient syntheses of target compounds for existing chemical series and novel series;
- Independently conduct multi-step synthesis and optimization through effective reaction planning, troubleshooting, and systematic analysis;
- Purify and characterize compounds using a variety of techniques including column chromatography, crystallization, trituration, LCMS, NMR, HPLC;
- Work under the supervision of the Director of Chemistry or the Project Manager in order to achieve the objectives of the project in line with those of the client;
- Research current literature to formulate synthetic and medicinal chemistry strategies. Evaluate and implement new reactions, techniques and technologies to advance the projects;
- Maintain lab notebook, instrument and inventory records in accord with department guidance;
- Maintain all appropriate standards for lab safety and hazardous material management.REQUIREMENTS:

- MSc in Organic Chemistry or Medicinal Chemistry;
- Strong knowledge and experience in current synthetic methods;
- Expertise in isolation and purification techniques such as silica gel chromatography and HPLC as well as modern analytical techniques such as NMR and LCMS;
- Knowledge of good laboratory and safety practices.
- Excellent written, organizational and documentation skills;
- Proactive with strong interpersonal skills; able to thrive in a team-based environment;
- Demonstrated ability to troubleshoot and creatively problem solve;
- Proficiency in Microsoft Office (Word, Excel and PowerPoint);
- Ability to communicate progress effectively with colleagues and managers**New employees will be required to provide proof of a complete COVID-19 vaccination;**:

- Applicants must be eligible to work in Canada (Canadian citizen, permanent resident or work permit).
- **COMPENSATION AND BENEFITS**:
**Salary**:

- Competitive and based on experience.

Additional pay:

- Annual bonus incentive plan.

**Advantages**:

- Full time permanent position;
- Health and dental care insurance plan;
- Short
- and long-term disability insurance;
- Life insurance;
- RRSP employer’s matching program;
- Casual dress code;
- Flexible schedule;
- On-site free parking;
- Continuing education;
- Career development.
- Salary is revised every year

Schedule:
French verion

ASSOCIÉ(E) DE RECHERCHE, CHIMIE

NuChem Sciences, une compagnie Sygnature Discovery est une organisation de recherche contractuelle de découverte de médicaments intégrée de premier plan basée au Royaume-Uni et au Canada avec son siège social à Nottingham et des installations supplémentaires à Alderley Park, Macclesfield, Glasgow, Montréal et Québec. Son personnel de plus de 1 000 personnes, dont 900 scientifiques, s’associe à l’industrie pharmaceutique mondiale, de biotechnologie et des organisations BNL.

RESPONSABILITÉS:

- Utiliser des méthodologies et de nouvelles techniques de synthèse pour concevoir et exécuter des synthèses efficaces de composés cibles pour des séries chimiques existantes et de nouvelles séries;
- Effectuer indépendamment l’optimisation des synthèses en plusieurs étapes grâce à une planification efficace des réactions, par la résolution de problème et par une analyse systématique;
- Purifier et caractériser les composés en utilisant une variété de techniques, y compris la chromatographie sur colonne, la cristallisation, la trituration, LCMS, RMN, HPLC;
- Travailler sous la supervision du Directeur de la chimie ou du Gestionnaire de projets afin d’atteindre les objectifs du projet en ligne avec ceux du client.
- Communiquer de façon efficiente les résultats.
- Tenir à jour le cahier de laboratoire, les instruments et les registres d'inventaire conformément aux directives;
- Maintenir toutes les normes appropriées pour la sécurité des laboratoires et la gestion des matières dangereuses.

QUALIFICATIONS:

- Maîtrise en chimie organique ou médicinale;
- Solides connaissances des méthodes de synthèses actuelles;
- Expérience dans les techniques d’isolement et de purification telles que la chromatographie sur gel de silice et HPLC ainsi que les techniques analytiques modernes telles que RMN, LCMS;
- Connaissance de bonnes pratiques de laboratoires;
- Excellentes capacités d'organisation, de documentation et de communication écrite et orale (français et anglais);
- Proactif avec de solides compétences interpersonnelles; capable de s'épanouir dans un environnement d'équipe;
- Capacité démon